RECRUITING

Electrical Impedance Myography: Natural History Studies inNeuromuscular Disorders and Healthy Volunteers

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: \- Electrical impedance myography (EIM) is a new technique being studied to see if it is helpful in evaluating muscle disorders and nerve disorders. EIM looks at how a mild, painless electrical current travels through muscles. Researchers want to gain experience in using the EIM device. They will collect information on the results of using it on people with and without nerve and muscle diseases, and compare that with information from other standard tests. First, they will test the device on healthy people. Then they will test people with a variety of neuromuscular diseases. Because the test is noninvasive and not painful, researchers will test both children and adults. Objectives: \- To gain experience using the EIM muscle testing device. Eligibility: * Healthy volunteers at least 2 years old. * Individuals at least 2 years old who have neuromuscular disease. Design: * Participants will be screened with a medical history and physical exam. * Participants will have one 2-3 hour clinic visit. Researchers may request follow-up visits. * Participants will be tested with the EIM device. The device and small electrodes will be placed on their skin. An electric current will pass through the device, but the participants will not feel this. * Participants may have an ultrasound test. A gel will be put on their skin, and a device will be moved over the skin. * Participants may have a nerve test. Electrodes will be placed on their skin, and they will feel a small shock. * Participants may have a test where a thin needle is inserted in their muscle.

Official Title

Electrical Impedance Myography: Natural History Studies in Neuromuscular Disorders and Healthy Volunteers

Quick Facts

Study Start:2013-06-20
Study Completion:2026-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT01900132

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:2 Years to 110 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Healthy adults, male or female, aged 18 years old or older,
  2. 2. In good general health as evidenced by medical history
  3. 3. Stated willingness to comply with all study procedures and availability for the duration of the study.
  4. 4. Ability of subject to understand and the willingness to sign a written informed consent document.
  5. 1. Healthy children, male or female, age 7-18,
  6. 2. In good general health as evidenced by medical history
  7. 3. Stated willingness to comply with all study procedures and availability for the duration of the study
  8. 4. Ability of subject or Legally Authorized Representative (LAR)) to understand and the willingness to sign a written informed consent document.
  9. 1. Suspected motor neuron disease or
  10. 2. Suspected myopathy or
  11. 3. Suspected neuropathy or
  12. 4. Suspected movement disorders that impair intracortical processes
  13. 5. Age of 2 years or older
  14. 6. Ability of subject to sign a written informed consent document.
  1. 1. Medical conditions that require medications that affects the physiological measures being tested. Some conditions that may be excluded are diabetes, kidney and liver disease.
  2. 2. History of stroke, muscle disorders, peripheral neuropathy or spine surgery
  3. 1. Medical conditions that require medications that affects the physiological measures being tested. Some conditions that may be excluded are diabetes, kidney and liver disease.
  4. 2. History of stroke, muscle disorders, peripheral neuropathy or spine surgery

Contacts and Locations

Study Contact

Candida Silva
CONTACT
(301) 496-7428
candida.silva@nih.gov
Tanya J Lehky, M.D.
CONTACT
(301) 496-7428
lehkyt@ninds.nih.gov

Principal Investigator

Tanya J Lehky, M.D.
PRINCIPAL_INVESTIGATOR
National Institute of Neurological Disorders and Stroke (NINDS)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)

  • Tanya J Lehky, M.D., PRINCIPAL_INVESTIGATOR, National Institute of Neurological Disorders and Stroke (NINDS)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2013-06-20
Study Completion Date2026-06-01

Study Record Updates

Study Start Date2013-06-20
Study Completion Date2026-06-01

Terms related to this study

Keywords Provided by Researchers

  • Electrophysiology
  • Neuromuscular Disease

Additional Relevant MeSH Terms

  • Neuromuscular Disease
  • Motor Neuron Disease
  • Inherited Neuromuscular Conditions
  • Inherited Neuropathies