Eye Pressure Lowering Surgery

Description

The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.

Conditions

Glaucoma

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Study Overview

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Study Details

Study overview

The purpose of this study is to determine if lowering the pressure inside the eye improves blood flow to the eye.

Observational Study of Ocular Blood Flow Pre- and Post- Glaucoma Surgery Using Functional and Structural Optical Coherence Tomography

Eye Pressure Lowering Surgery

Condition
Glaucoma
Intervention / Treatment

-

Contacts and Locations

Portland

OHSU, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Subjects diagnosed with perimetric open angle glaucoma or chronic angle closure glaucoma.
  • * Subjects scheduled to undergo trabeculectomy or tube shunt surgery
  • * Best-corrected visual acuity less than 20/40
  • * Age \< 18 or \>85 years
  • * Refractive error of \> +3.00 D or \< -7.00 D
  • * Previous vision correction surgery such as Laser-Assisted in situ Keratomileusis (LASIK) or Photorefractive Keratectomy (PRK)
  • * Previous intraocular surgery except for uncomplicated cataract extraction with posterior chamber intraocular lens implantation
  • * Diabetic retinopathy
  • * History of heart failure, myocardial infarction, transient ischemic attack or stroke
  • * Other diseases that may cause VF loss or optic disc abnormalities
  • * Inability to clinically view or photograph the optic discs due to media opacity or poorly dilating pupil
  • * Inability to perform reliably on automated VF testing
  • * Life-threatening or debilitating illness making it unlikely patient will successfully complete the study.
  • * Refusal of informed consent or of commitment to the full length of the study

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

Aiyin Chen, MD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2026-05