Optical Coherence Tomography (OCT) in Uveitis

Description

Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer (one one-thousandths) scale imaging of biological tissue. This allows excellent assessment of the white blood and inflammatory cells seen in uveitis, an inflammation of any or all parts of the uvea (iris, ciliary body, choroid).

Conditions

Uveitis

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Study Overview

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Study Details

Study overview

Optical Coherence Tomography (OCT) machines are non-contact instruments that can provide micrometer (one one-thousandths) scale imaging of biological tissue. This allows excellent assessment of the white blood and inflammatory cells seen in uveitis, an inflammation of any or all parts of the uvea (iris, ciliary body, choroid).

Objective Grading of Intraocular Inflammation in Uveitis Using Optical Coherence Tomography

Optical Coherence Tomography (OCT) in Uveitis

Condition
Uveitis
Intervention / Treatment

-

Contacts and Locations

Portland

Oregon Health & Science University, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 years of age and older
  • * With one or more of the following clinical features:
  • 1. \>1+ AC cells;
  • 2. \>1+ vitreous haze;
  • 3. presence of vitreous cells;
  • 4. presence of blood in anterior chamber;
  • 5. presence of blood in vitreous;
  • 6. presence of aqueous or vitreous pigment.
  • * In one of the following diagnostic categories as determined by a uveitis specialists:
  • 1. uveitis due to ankylosing spondylitis (positive HLA B27 genotype);
  • 2. uveitis due to sarcoidosis;
  • 3. uveitis of any additional type;
  • 4. uveitis masquerade such as pigment dispersion syndrome or Schaffer's sign;
  • 5. hyphema due to trauma or other causes;
  • 6. vitreous hemorrhage;
  • 7. retinal tear.
  • * Inability to give informed consent;
  • * Inability to maintain stable fixation for OCT imaging.

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

David Huang, MD, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2025-12