RECRUITING

Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for overweight and obese individuals. The driving hypothesis of the clinic is that the 'one size fits all' philosophy is untenable with a complex disease such as obesity. The clinic will serve as a portal for patients to choose standard clinical care or to explore alternatives from a variety of clinical studies offered through the clinic. These studies will include further investigations into nutrition, the biological basis of weight and weight management and protocols using approved and experimental pharmaceuticals as well as technologies that aid in self-management of weight.

Official Title

Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance

Quick Facts

Study Start:2009-08
Study Completion:2025-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02043457

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:15 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Obese males and females: age \>20 years; Obese population defined as BMI \> or = 27 kg/m2
  2. * Lean population BMI \< 27 but \> 17 kg/m2
  3. * Able and willing to provide written informed consent for the trial
  1. * Evidence of inherited disorders of lipid metabolism.
  2. * History of Cancer within the last 5 years
  3. * Human immunodeficiency virus (HIV) antibody positive.
  4. * Patients with solid organ transplants.
  5. * Participation in any other clinical trial within 90 days of entry into this trial.
  6. * Pregnant or lactating females.
  7. * Uncontrolled thyroid disease
  8. * Unstable angina or NY heart association class II failure or above
  9. * Gastrointestinal disease specifically GI motility disorders
  10. * Unstable neuropsychiatric disease including major depression/anxiety, eating disorder such as binge eating, bulimia or anorexia
  11. * End stage renal or hepatic disease
  12. * Autoimmune disorders (e.g. SLE)
  13. * Body weight fluctuation of more than 5 kg in the previous 3 months
  14. * Prior bariatric surgery
  15. * A history or current alcohol/substance abuse and change in smoking habits or cessation in the past 6 months.
  16. * Women of childbearing age must use a reliable form of contraception.
  17. * Any medical condition, which in the opinion of the investigator would make the patient unsuitable for recruitment, or could interfere with the patient participating in or completing the protocol.
  18. * Unwilling or unable to consent for the study.

Contacts and Locations

Study Contact

Amy E Rothberg, MD, PhD
CONTACT
734-647-5871
arothber@med.umich.edu

Principal Investigator

Charles Burant, MD, PhD
STUDY_DIRECTOR
University of Michigan

Study Locations (Sites)

University of Michigan
Ann Arbor, Michigan, 48106
United States

Collaborators and Investigators

Sponsor: University of Michigan

  • Charles Burant, MD, PhD, STUDY_DIRECTOR, University of Michigan

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2009-08
Study Completion Date2025-12

Study Record Updates

Study Start Date2009-08
Study Completion Date2025-12

Terms related to this study

Additional Relevant MeSH Terms

  • Obesity