Observational Study of Corneal Opacities in Adults

Description

A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT will be used to perform 3-D corneal scans. These scans will be used to assess opacity depth and measure corneal thickness (pachymetry), corneal topography (anterior and posterior), and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imaging, will be performed for comparison.

Conditions

Corneal Opacities (Scar and Stromal Dystrophy)

Study Overview

Study Details

Study overview

A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT will be used to perform 3-D corneal scans. These scans will be used to assess opacity depth and measure corneal thickness (pachymetry), corneal topography (anterior and posterior), and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imaging, will be performed for comparison.

Observational Study of Corneal Opacities in Adults

Observational Study of Corneal Opacities in Adults

Condition
Corneal Opacities (Scar and Stromal Dystrophy)
Intervention / Treatment

-

Contacts and Locations

Portland

Humberto Martinez, Portland, Oregon, United States, 97239

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Inability to give informed consent.
  • * Inability to maintain stable fixation for OCT imaging.
  • * Inability to commit to required visits to complete the study.

Ages Eligible for Study

18 Years to 100 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Oregon Health and Science University,

David Huang, MD, PhD, PRINCIPAL_INVESTIGATOR, Oregon Health and Science University

Study Record Dates

2025-12