Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

Description

This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy (ART) on young adults with perinatal HIV infection (YAPHIV) as they transition into adulthood. A group of of perinatally exposed but uninfected young adults from a similar sociodemographic background and age distribution will be enrolled for comparison.

Conditions

HIV/AIDS

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Study Overview

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Study Details

Study overview

This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy (ART) on young adults with perinatal HIV infection (YAPHIV) as they transition into adulthood. A group of of perinatally exposed but uninfected young adults from a similar sociodemographic background and age distribution will be enrolled for comparison.

Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

Condition
HIV/AIDS
Intervention / Treatment

-

Contacts and Locations

La Jolla

University of California San Diego, La Jolla, California, United States, 92093

Aurora

University of Colorado Denver Health Sciences Center, Aurora, Colorado, United States, 80045

Fort Lauderdale

Children's Diagnostic and Treatment Center, Fort Lauderdale, Florida, United States, 33316

Miami

University of Miami, Miami, Florida, United States, 33316

Chicago

Ann and Robert H. Lurie Children's Hospital, Chicago, Illinois, United States, 60614

New Orleans

Tulane University Health Sciences Center, New Orleans, Louisiana, United States, 70112

Boston

Children's Hospital Boston, Boston, Massachusetts, United States, 02115

Newark

Rutgers - New Jersey Medical School, Newark, New Jersey, United States, 07101

Bronx

Bronx Lebanon Hospital Center, Bronx, New York, United States, 10457

Bronx

Jacobi Medical Center, Bronx, New York, United States, 10461

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Perinatal HIV infection as documented in the medical record
  • * At or beyond their 18th birthday at the time of informed consent with no upper age limit
  • * Willing to provide access to existing medical records
  • * Available medical record documentation since early childhood of:
  • * ART exposure history
  • * Opportunistic infection prophylaxis exposure history
  • * Viral load and CD4+ cell count history
  • * Major medical events history
  • * Willingness to participate and provide legal written consent
  • * HIV acquired by other than maternal-child transmission (e.g., blood products, sexual contact, and IV drug use) as documented in the medical record

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Harvard School of Public Health (HSPH),

Paige L Williams, PRINCIPAL_INVESTIGATOR, Harvard School of Public Health (HSPH)

Russell Van Dyke, MD, PRINCIPAL_INVESTIGATOR, Tulane University School of Medicine

Katherine Tassiopoulos, DSc, MPH, PRINCIPAL_INVESTIGATOR, Harvard School of Public Health (HSPH)

Study Record Dates

2025-07