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Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

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Conditions

HIV/AIDSHIV/AIDS, perinatal HIV infection

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is a prospective cohort study designed to define the impact of HIV infection and antiretroviral therapy (ART) on young adults with perinatal HIV infection (YAPHIV) as they transition into adulthood. A group of of perinatally exposed but uninfected young adults from a similar sociodemographic background and age distribution will be enrolled for comparison.

Official Title

Adolescent Master Protocol for Participants 18 Years of Age and Older (AMP Up)

Quick Facts

Study Start:2014-04
Study Completion:2025-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT02119702

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Perinatal HIV infection as documented in the medical record
  2. * At or beyond their 18th birthday at the time of informed consent with no upper age limit
  3. * Willing to provide access to existing medical records
  4. * Available medical record documentation since early childhood of:
  5. * ART exposure history
  6. * Opportunistic infection prophylaxis exposure history
  7. * Viral load and CD4+ cell count history
  8. * Major medical events history
  9. * Willingness to participate and provide legal written consent
  1. * HIV acquired by other than maternal-child transmission (e.g., blood products, sexual contact, and IV drug use) as documented in the medical record

Contacts and Locations

Principal Investigator

Paige L Williams
PRINCIPAL_INVESTIGATOR
Harvard School of Public Health (HSPH)
Russell Van Dyke, MD
PRINCIPAL_INVESTIGATOR
Tulane University School of Medicine
Katherine Tassiopoulos, DSc, MPH
PRINCIPAL_INVESTIGATOR
Harvard School of Public Health (HSPH)

Study Locations (Sites)

University of California San Diego
La Jolla, California, 92093
United States
University of Colorado Denver Health Sciences Center
Aurora, Colorado, 80045
United States
Children's Diagnostic and Treatment Center
Fort Lauderdale, Florida, 33316
United States
University of Miami
Miami, Florida, 33316
United States
Ann and Robert H. Lurie Children's Hospital
Chicago, Illinois, 60614
United States
Tulane University Health Sciences Center
New Orleans, Louisiana, 70112
United States
Children's Hospital Boston
Boston, Massachusetts, 02115
United States
Rutgers - New Jersey Medical School
Newark, New Jersey, 07101
United States
Bronx Lebanon Hospital Center
Bronx, New York, 10457
United States
Jacobi Medical Center
Bronx, New York, 10461
United States
St. Christopher's Hospital for Children
Philadelphia, Pennsylvania, 19134
United States
St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
United States
Baylor College of Medicine
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: Harvard School of Public Health (HSPH)

  • Paige L Williams, PRINCIPAL_INVESTIGATOR, Harvard School of Public Health (HSPH)
  • Russell Van Dyke, MD, PRINCIPAL_INVESTIGATOR, Tulane University School of Medicine
  • Katherine Tassiopoulos, DSc, MPH, PRINCIPAL_INVESTIGATOR, Harvard School of Public Health (HSPH)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2014-04
Study Completion Date2025-05-31

Study Record Updates

Study Start Date2014-04
Study Completion Date2025-05-31

Terms related to this study

Keywords Provided by Researchers

  • HIV/AIDS, perinatal HIV infection

Additional Relevant MeSH Terms

  • HIV/AIDS