RECRUITING

Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is twofold. First, is to determine whether vancomycin is effective in the early treatment of Biliary Atresia (BA) and Primary Sclerosing Cholangitis (PSC), and if so, by what mechanism. Secondly, to characterize human intestinal microbial communities and their interactions with the host.

Official Title

The Human Gastrointestinal Tract Microbiota in the Setting of Treating Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin

Quick Facts

Study Start:2010-07
Study Completion:2028-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02137668

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:2 Weeks to 40 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Persons who have primary sclerosing cholangitis, biliary atresia, a chronic intestinal disorder or who are undergoing upper or lower endoscopy.
  2. * Persons who have primary sclerosing cholangitis or biliary atresia who are good candidates for vancomycin therapy.
  1. * Patients that have taken antibiotics and/or immunomodulators within the last 3 months will be excluded as this will alter the original bacterial flora.
  2. * Females who are pregnant may not participate.

Contacts and Locations

Principal Investigator

Yinka Davies, M.D.
PRINCIPAL_INVESTIGATOR
Sacramento Pediatric Gastroenterology

Study Locations (Sites)

Sacramento Pediatric Gastroenterology
Sacramento, California, 95841
United States

Collaborators and Investigators

Sponsor: Sacramento Pediatric Gastroenterology

  • Yinka Davies, M.D., PRINCIPAL_INVESTIGATOR, Sacramento Pediatric Gastroenterology

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2010-07
Study Completion Date2028-07

Study Record Updates

Study Start Date2010-07
Study Completion Date2028-07

Terms related to this study

Additional Relevant MeSH Terms

  • Primary Sclerosing Cholangitis
  • Biliary Atresia