Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

Description

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among infants living with HIV.

Conditions

HIV Infection

Study Overview

Study Details

Study overview

The study will explore the effects of early intensive antiretroviral therapy (ART) with or without a broadly neutralizing antibody (bNAb) on achieving HIV remission (HIV RNA below the limit of detection of the assay) among infants living with HIV.

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission: A Phase I/II Proof of Concept Study

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

Condition
HIV Infection
Intervention / Treatment

-

Contacts and Locations

La Jolla

4601, University of California, San Diego Clinical Research Site, La Jolla, California, United States, 92093-0672

Los Angeles

5048, University of Southern California Clinical Research Site, Los Angeles, California, United States, 90089

Los Angeles

5112, David Geffen School of Medicine at UCLA Clinical Research Site, Los Angeles, California, United States, 90095-1752

Aurora

5052, University of Colorado, Denver Clinical Research Site, Aurora, Colorado, United States, 80045

Fort Lauderdale

5055, South Florida CDTC Fort Lauderdale Clinical Research Site, Fort Lauderdale, Florida, United States, 33316

Jacksonville

5051, University of Florida Center for HIV/AIDS Research, Education and Service (UF CARES) Clinical Research Site, Jacksonville, Florida, United States, 32209

Miami

5127, Pediatric Perinatal HIV Clinical Research Site, Miami, Florida, United States, 33136

Miami

University of Miami CRS, Miami, Florida, United States, 33136

Atlanta

Emory University School of Medicine NICHD CRS, Atlanta, Georgia, United States, 30322

Chicago

5083, Rush University Cook County Hospital Clinical Research Site, Chicago, Illinois, United States, 60612

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    to 48 Hours

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    National Institute of Allergy and Infectious Diseases (NIAID),

    Ellen Chadwick, MD, STUDY_CHAIR, Northwestern University Feinberg School of Medicine and Ann & Robert Lurie Children's Hospital of Chicago

    Jennifer Jao, MD, STUDY_CHAIR, Northwestern University Feinberg School of Medicine and Ann & Robert Lurie Children's Hospital of Chicago

    Study Record Dates

    2031-12-31