Molecular Autopsy Study

Description

This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.

Conditions

Sudden Unexplained Death

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Study Overview

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Study Details

Study overview

This study seeks to incorporate genetic testing into the postmortem examination of cases of sudden unexplained death.

Molecular Autopsy for Sudden Cardiovascular Death

Molecular Autopsy Study

Condition
Sudden Unexplained Death
Intervention / Treatment

-

Contacts and Locations

La Jolla

Scripps Translational Science Institute, La Jolla, California, United States, 92037

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Index case age between birth - 45 years
  • * Clinical presentation of sudden / unexplained death (believed to be cardiac in nature OR secondary to a massive unprovoked pulmonary embolism with no prior diagnosis of prothrombotic disease)
  • * Premature death secondary to murder, suicide or external causal event
  • * Premature death thought secondary to known chronic comorbid medical condition
  • * Premature death thought secondary to end-organ failure (kidney, liver, lung) other than heart
  • * Previously diagnosed with hypertrophic cardiomyopathy (HCM)
  • * Prior myocardial infarction (regardless of stenting or bypass)
  • * Prior cerebrovascular accident (stroke or TIA)
  • * History of open heart surgery (for any reason)
  • * History of severe, untreated hypertensive heart disease
  • * History of illicit drug use
  • * History of heavy alcohol abuse
  • * History of severe pulmonary disease
  • * History of morbid obesity

Ages Eligible for Study

to 45 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Scripps Translational Science Institute,

Study Record Dates

2030-06