COMPLETED

Detection of Brown Adipose Tissue by Magnetic Resonance Imaging

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The primary goal of this study is to assess the accuracy of conventional fat fraction proton MRI for the detection of Brown Adipose Tissue (BAT) in healthy subjects using \[18F\]-2-fluoro-2-deoxy-D-glucose (fluorodeoxyglucose) -PET as gold standard. In this pilot study, MRI and PET imaging of BAT of healthy adult volunteers will be performed on a combined PET/MRI scanner under mild cold condition.

Official Title

Assessment of MRI Accuracy for the Detection of Brown Adipose Tissue Using [18F]-2-fluoro-2-deoxy-D-glucose (Fluorodeoxyglucose) -PET as a Gold Standard

Quick Facts

Study Start:2015-01-20
Study Completion:2015-08-27
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT02237872

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Each subject must be fully informed and have signed consent.
  2. * BMI \< 34
  3. * Normal neurological and psychological development / able to give consent
  4. * Willingness to participate in this study
  1. * Subjects less than 18 years of age
  2. * Severe claustrophobia
  3. * Women who are pregnant, nursing an infant or planning to become pregnant in the next 30 days
  4. * People who have a condition that makes MRI unsafe for them (for example, cardiac pacemaker, epicardial pacemaker leads, cochlear implants, metal aneurysm clip, iron filings in your eyes or metal halo devices)
  5. * Have had radiation therapy or chemotherapy in the 2 months prior to PET scan
  6. * Subjects are taking medications that may interfere with BAT detection

Contacts and Locations

Principal Investigator

Rosa Tamara Branca, PhD
PRINCIPAL_INVESTIGATOR
University of North Carolina, Chapel Hill

Study Locations (Sites)

Biomedical Research Imaging Center
Chapel Hill, North Carolina, 27599-7513
United States
Biomedical Research Imaging Center
Chapel Hill, North Carolina, 27599
United States

Collaborators and Investigators

Sponsor: University of North Carolina, Chapel Hill

  • Rosa Tamara Branca, PhD, PRINCIPAL_INVESTIGATOR, University of North Carolina, Chapel Hill

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2015-01-20
Study Completion Date2015-08-27

Study Record Updates

Study Start Date2015-01-20
Study Completion Date2015-08-27

Terms related to this study

Keywords Provided by Researchers

  • Brown Adipose Tissue
  • MRI and PET detection of brown adipose tissue

Additional Relevant MeSH Terms

  • Obesity
  • Brown Adipose Tissue