Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

Description

This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with cancer in the laboratory may help doctors learn more about how inherited genetic mutations can affect cancer predisposition (an inherited increase in the risk of developing cancer), their impact on treatment response, and their role in cancer development.

Conditions

Malignant Neoplasm

Study Overview

Study Details

Study overview

This research trial studies germ-line mutations in blood and saliva samples from patients with cancer. Studying samples of blood and saliva from patients with cancer in the laboratory may help doctors learn more about how inherited genetic mutations can affect cancer predisposition (an inherited increase in the risk of developing cancer), their impact on treatment response, and their role in cancer development.

An Investigation of the Role of Germ-Line Mutations in Cancer Predisposition, Tumor Biology, and Response to Treatment

Germ-Line Mutations in Blood and Saliva Samples From Patients With Cancer

Condition
Malignant Neoplasm
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Jonsson Comprehensive Cancer Center, Los Angeles, California, United States, 90095

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Pathologically or clinical confirmed tissue diagnosis of a cancer
  • * Ability to understand and the willingness to sign a written informed consent
  • * Patients will be excluded if their cancer cannot be confirmed
  • * Refusal to sign the informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Jonsson Comprehensive Cancer Center,

Joanne Weidhaas, PRINCIPAL_INVESTIGATOR, Jonsson Comprehensive Cancer Center

Study Record Dates

2026-09-16