Sensory-Motor Rehabilitation Post Stroke

Description

Early after stroke, patients often have significant motor impairment and sensory deficit. Evidence has demonstrated heightened plasticity and significant recovery in the acute phase (first months) post stroke but there has been a lack of effective and practical protocols and devices for early intensive sensorimotor therapy.This research study will conduct a randomized clinical trial of an intensive motor-sensory rehabilitation on patients with acute stroke using a wearable rehabilitation robot. The primary aims are to facilitate sensorimotor recovery, reduce ankle impairments, and improve balance and gait functions. This clinical trial will be conducted on the Study and Control groups of acute stroke survivors.

Conditions

Acute Stroke

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Study Overview

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Study Details

Study overview

Early after stroke, patients often have significant motor impairment and sensory deficit. Evidence has demonstrated heightened plasticity and significant recovery in the acute phase (first months) post stroke but there has been a lack of effective and practical protocols and devices for early intensive sensorimotor therapy.This research study will conduct a randomized clinical trial of an intensive motor-sensory rehabilitation on patients with acute stroke using a wearable rehabilitation robot. The primary aims are to facilitate sensorimotor recovery, reduce ankle impairments, and improve balance and gait functions. This clinical trial will be conducted on the Study and Control groups of acute stroke survivors.

Sensory-Motor Rehabilitation Post Stroke

Sensory-Motor Rehabilitation Post Stroke

Condition
Acute Stroke
Intervention / Treatment

-

Contacts and Locations

Baltimore

University of Maryland, Baltimore, Baltimore, Maryland, United States, 21201

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. First time unilateral acute stroke, hemorrhagic or ischemic, 24 hours after admission in hospital to 1 year post stroke.
  • 2. Hemiplegia or hemiparesis
  • 3. Age 18-80
  • 4. Ankle impairments
  • 1. No impairment or very mild ankle impairment of ankle.
  • 2. Unstable medical conditions that interferes with ability to training and exercise.
  • 3. Severe cardiovascular disorders that interfere with ability to perform moderate movement exercises.
  • 4. Cognitive impairment or aphasia with inability to follow instructions
  • 5. Pressure ulcer, recent surgical incision or active skin disease with open wounds present below knee of treated limb
  • 6. Severe pain in legs

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Maryland, Baltimore,

Li-Qun Zhang, Ph.D., PRINCIPAL_INVESTIGATOR, University of Maryland, Baltimore

Study Record Dates

2025-12-31