Peripheral Blood Flow Responses to Electromagnetic Energy

Description

This study evaluates 670 nm energy in the form of red light to stimulate blood flow changes in healthy adults. All participants will receive red light to their leg. They will also receive a continuous infusion of Definity (octafluoropropane) ultrasound contrast.

Conditions

Exposure to Man-made Visible Light

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Study Overview

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Study Details

Study overview

This study evaluates 670 nm energy in the form of red light to stimulate blood flow changes in healthy adults. All participants will receive red light to their leg. They will also receive a continuous infusion of Definity (octafluoropropane) ultrasound contrast.

Peripheral Blood Flow Responses to Electromagnetic Energy

Peripheral Blood Flow Responses to Electromagnetic Energy

Condition
Exposure to Man-made Visible Light
Intervention / Treatment

-

Contacts and Locations

Milwaukee

Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 53226

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Participants will be healthy subjects over the age of 18.
  • * Men and women will be recruited for participation.
  • * All ethnicities will be included in this study.
  • * age under 18 years and those over 60 years of age,
  • * those who are unable to understand the consent process,
  • * those who cannot read or speak English,
  • * a history of cancer,
  • * peripheral artery disease,
  • * diabetes mellitus,
  • * active pregnancy,
  • * hypersensitivity to perflutren contrast agents,
  • * pulmonary hypertension,
  • * chronic kidney disease,
  • * active tobacco or drug use,
  • * blood pressure over 160/90, BMI\>30,
  • * sickle cell disease, or
  • * history of intracardiac shunt.
  • * a history of coronary artery disease,
  • * heart failure,
  • * the presence of an implanted defibrillator or pacemaker,
  • * a history of heart murmur or rhythm disorder (atrial fibrillation, atrial tachycardia, or ventricular tachycardia),
  • * neurological diseases such as stroke, and
  • * any uncontrolled medical conditions.

Ages Eligible for Study

18 Years to 59 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Alabama at Birmingham,

Nicole L Lohr, MD, PhD, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

2025-05-01