Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

Description

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.

Conditions

Abdominal Aortic Aneurysm

Study Overview

Study Details

Study overview

The main objective of this study is to utilize Magnetic Resonance Elastography (MRE) to determine tissue stiffness of abdominal aortic aneurysms (AAA). For patients with AAA, MRE is a more sensitive and superior method of determining the risk for rupture of AAA based on stiffness estimates when compared to the current, crude method of assessing risk based on measurement of the diameter of the aneurysm. The investigators will also validate the stiffness estimates against gold standard i.e. mechanical testing and histopathology only AAA patients undergoing AAA surgery.

Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms

Condition
Abdominal Aortic Aneurysm
Intervention / Treatment

-

Contacts and Locations

Columbus

The Ohio State University Medical Center, Columbus, Ohio, United States, 43210

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Must be able to lie flat on their back in the scanner for up to 60 minutes
  • * Must be able to hold breath for up to 15 seconds
  • * Patients who are claustrophobic
  • * Patients who are pregnant
  • * Patients with any unapproved, non-MRI save metal/devices in or on their body

Ages Eligible for Study

20 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Ohio State University,

Arunark Kolipaka, PhD, PRINCIPAL_INVESTIGATOR, The Ohio State University Medical Center Dept. of Radiology

Study Record Dates

2026-10-31