RECRUITING

Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Background: \- Computed Tomography (CT) is a scan that makes detailed pictures of the body. It uses radiation to do that. In 2011, about 85.3 million CT scans were done in the United States. But there is growing concern about the health effects of radiation. There are new and different ways to make CT pictures that use less radiation. Researchers want to learn whether these new methods create images that are similar to images from a traditional CT. Objective: \- To learn if new CT imaging methods with less radiation make images that are similar to traditional ways. Eligibility: \- Adults 18 years of age and older who are scheduled for a CT of the chest, abdomen and pelvis with contrast. Design: * Researchers will review participants medical records to see if they can be in this study. * Participants may have blood drawn from an arm vein by a needle stick. The blood will be used to make sure they can be in this study and that it is safe for them to have contrast. * During the participants CT scan appointment, one extra scan will be done using low radiation methods. * During a CT scan, the participant lies on a table. A large x-ray machine takes pictures of the body.

Official Title

Prospective Evaluation of Next Generation CT Reconstruction

Quick Facts

Study Start:2014-09-08
Study Completion:2026-07-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02417714

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 99 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Clinical indication for a chest, abdomen and pelvis CT with contrast
  2. 2. Age equal to or greater than 18 years
  3. 3. Able to understand and willing to sign the Informed Consent Form
  4. 1. Clinical indication for a CT with or without contrast that includes the chest
  5. 2. Age equal to or greater than 18 years
  6. 3. Able to understand and willing to sign the Informed Consent Form
  1. 1. Pregnancy
  2. 2. Serum Cr \> 1.5 mg/dL
  3. 3. Clinical CT scan with more than one contrast imaging phase (for example three phase liver)

Contacts and Locations

Study Contact

Margaret C Lowery, R.N.
CONTACT
(301) 451-3128
peg.lowery@nih.gov
Marcus Y Chen, M.D.
CONTACT
(301) 496-0077
chenmy@mail.nih.gov

Principal Investigator

Marcus Y Chen, M.D.
PRINCIPAL_INVESTIGATOR
National Heart, Lung, and Blood Institute (NHLBI)

Study Locations (Sites)

National Institutes of Health Clinical Center
Bethesda, Maryland, 20892
United States

Collaborators and Investigators

Sponsor: National Heart, Lung, and Blood Institute (NHLBI)

  • Marcus Y Chen, M.D., PRINCIPAL_INVESTIGATOR, National Heart, Lung, and Blood Institute (NHLBI)

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2014-09-08
Study Completion Date2026-07-01

Study Record Updates

Study Start Date2014-09-08
Study Completion Date2026-07-01

Terms related to this study

Keywords Provided by Researchers

  • Computed Tomography
  • Radiation Reduction
  • Iterative Reconstruction
  • Natural History

Additional Relevant MeSH Terms

  • Healthy Subjects