RECRUITING

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder. The knowledge gained from the analysis of this information will provide the basis for future genetic counseling as well as contribute to knowledge about the biology of normal and abnormal development of left-right anatomic asymmetry.

Official Title

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Quick Facts

Study Start:2009-07
Study Completion:2030-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02432079

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Subjects with heterotaxy and related congenital heart defects
  2. * Family members of subjects with heterotaxy and related congenital heart defects
  1. * Subjects without heterotaxy and related congenital heart defects
  2. * Family members of subjects without heterotaxy and related congenital heart defects

Contacts and Locations

Study Contact

Lindsey R. Helvaty, BA, BS
CONTACT
317-278-3020
lhelvaty@iu.edu
Stephanie M. Ware, MD, PhD
CONTACT
317-278-2807
stware@iu.edu

Principal Investigator

Stephanie M. Ware, MD, PhD
PRINCIPAL_INVESTIGATOR
Indiana University School of Medicine

Study Locations (Sites)

Indiana University School of Medicine
Indianapolis, Indiana, 46202
United States

Collaborators and Investigators

Sponsor: Indiana University

  • Stephanie M. Ware, MD, PhD, PRINCIPAL_INVESTIGATOR, Indiana University School of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2009-07
Study Completion Date2030-12

Study Record Updates

Study Start Date2009-07
Study Completion Date2030-12

Terms related to this study

Keywords Provided by Researchers

  • Abnormalities, Multiple
  • Asplenia
  • Bilary Atresia
  • Birth Defect
  • Cardiovascular Abnormalities
  • Cardiovascular Diseases
  • Congenital Abnormalities
  • Congenital Heart Disease
  • Dextrocardia Syndrome
  • Disturbed Internal Organ Positioning
  • Genetics
  • Genetic Testing
  • Heart Defects, Congenital
  • Heart Diseases
  • Heterotaxy syndrome
  • Intestinal malrotation
  • Laterality
  • Left Atrial Isomerism
  • Pediatrics
  • Polysplenia
  • Right Atrial Isomerism
  • Splenic Diseases
  • Cilia
  • Situs inversus
  • Dextrocardia

Additional Relevant MeSH Terms

  • Heterotaxy Syndrome
  • Congenital Heart Defects