Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Description

The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder. The knowledge gained from the analysis of this information will provide the basis for future genetic counseling as well as contribute to knowledge about the biology of normal and abnormal development of left-right anatomic asymmetry.

Conditions

Heterotaxy Syndrome, Congenital Heart Defects

Study Overview

Study Details

Study overview

The goal of this study is to obtain specimens and data from individuals and their families with heterotaxy and related congenital heart defects in order to clarify the molecular genetics of this disorder. The knowledge gained from the analysis of this information will provide the basis for future genetic counseling as well as contribute to knowledge about the biology of normal and abnormal development of left-right anatomic asymmetry.

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Molecular Genetics of Heterotaxy and Related Congenital Heart Defects

Condition
Heterotaxy Syndrome
Intervention / Treatment

-

Contacts and Locations

Indianapolis

Indiana University School of Medicine, Indianapolis, Indiana, United States, 46202

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Subjects with heterotaxy and related congenital heart defects
  • * Family members of subjects with heterotaxy and related congenital heart defects
  • * Subjects without heterotaxy and related congenital heart defects
  • * Family members of subjects without heterotaxy and related congenital heart defects

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Indiana University,

Stephanie M. Ware, MD, PhD, PRINCIPAL_INVESTIGATOR, Indiana University School of Medicine

Study Record Dates

2030-12