Biomarkers in Friedreich's Ataxia

Description

The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.

Conditions

Friedreich's Ataxia

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Study Overview

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Study Details

Study overview

The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.

Biomarkers in Friedreich's Ataxia

Biomarkers in Friedreich's Ataxia

Condition
Friedreich's Ataxia
Intervention / Treatment

-

Contacts and Locations

Gainesville

University of Florida, Gainesville, Florida, United States, 32610

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Genetic diagnosis of Friedreich's ataxia by DNA sequencing, mutational analysis or protein assay OR be a healthy subject with no evidence of a neuromuscular disorder
  • * Between the ages of 8 and 70 (inclusive)
  • * Are able to tolerate metabolic exercise testing
  • * Are stable on cardiac medication regimen for 3 months prior to screening
  • * Presence of unstable heart disease
  • * Receipt of cardiac transplant
  • * Any concurrent medical condition which, in the opinion of the investigators, would make the subject unsuitable for the study

Ages Eligible for Study

8 Years to 70 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Florida,

Manuela Corti, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

2030-06-03