RECRUITING

Biomarkers in Friedreich's Ataxia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this project is to characterize measures of cardiac performance and neuromuscular physiology in FA patients using novel techniques, including echocardiography and magnetic resonance imaging (MRI), metabolic exercise testing, and neurophysiological outcomes.

Official Title

Biomarkers in Friedreich's Ataxia

Quick Facts

Study Start:2015-09
Study Completion:2030-06-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02497534

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:8 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Genetic diagnosis of Friedreich's ataxia by DNA sequencing, mutational analysis or protein assay OR be a healthy subject with no evidence of a neuromuscular disorder
  2. * Between the ages of 8 and 70 (inclusive)
  3. * Are able to tolerate metabolic exercise testing
  4. * Are stable on cardiac medication regimen for 3 months prior to screening
  1. * Presence of unstable heart disease
  2. * Receipt of cardiac transplant
  3. * Any concurrent medical condition which, in the opinion of the investigators, would make the subject unsuitable for the study

Contacts and Locations

Study Contact

Mackenzi Coker, M.S.CCC-SLP
CONTACT
352-294-8754
mcoker@peds.ufl.edu

Principal Investigator

Manuela Corti, PT, PhD
PRINCIPAL_INVESTIGATOR
University of Florida

Study Locations (Sites)

University of Florida
Gainesville, Florida, 32610
United States

Collaborators and Investigators

Sponsor: University of Florida

  • Manuela Corti, PT, PhD, PRINCIPAL_INVESTIGATOR, University of Florida

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2015-09
Study Completion Date2030-06-03

Study Record Updates

Study Start Date2015-09
Study Completion Date2030-06-03

Terms related to this study

Keywords Provided by Researchers

  • ataxia
  • neuromuscular

Additional Relevant MeSH Terms

  • Friedreich's Ataxia