RECRUITING

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study visits and complete questionnaires.

Official Title

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Quick Facts

Study Start:2015-06
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02502162

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Upper and/or lower extremity CRPS
  2. * On stable treatment for 1 month
  3. * CRPS for at least 1 year
  4. * Meet the Budapest criteria for CRPS at time of the study.
  1. * Any known allergy to naltrexone or naloxone
  2. * Use of prescription opioid analgesics or illegal opioid use
  3. * Current or planned pregnancy.

Contacts and Locations

Study Contact

Birute Gedrimaite
CONTACT
(650) 497-0485
birute@stanford.edu

Principal Investigator

Sean Mackey, MD, PhD
PRINCIPAL_INVESTIGATOR
Stanford University

Study Locations (Sites)

Stanford University
Palo Alto, California, 94304
United States

Collaborators and Investigators

Sponsor: Stanford University

  • Sean Mackey, MD, PhD, PRINCIPAL_INVESTIGATOR, Stanford University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2015-06
Study Completion Date2025-06

Study Record Updates

Study Start Date2015-06
Study Completion Date2025-06

Terms related to this study

Additional Relevant MeSH Terms

  • Complex Regional Pain Syndrome