This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma that is growing, spreading, or getting worse (progressive). Vismodegib, FAK inhibitor GSK2256098, capivasertib, and abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Intracranial Meningioma, Recurrent Meningioma, NF2 Gene Mutation
This phase II trial studies how well vismodegib, focal adhesion kinase (FAK) inhibitor GSK2256098, and capivasertib work in treating patients with meningioma that is growing, spreading, or getting worse (progressive). Vismodegib, FAK inhibitor GSK2256098, capivasertib, and abemaciclib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Vismodegib, FAK Inhibitor GSK2256098, Capivasertib, and Abemaciclib in Treating Patients With Progressive Meningiomas
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University of Alabama at Birmingham Cancer Center, Birmingham, Alabama, United States, 35233
Anchorage Associates in Radiation Medicine, Anchorage, Alaska, United States, 98508
Anchorage Radiation Therapy Center, Anchorage, Alaska, United States, 99504
Alaska Breast Care and Surgery LLC, Anchorage, Alaska, United States, 99508
Alaska Oncology and Hematology LLC, Anchorage, Alaska, United States, 99508
Alaska Women's Cancer Care, Anchorage, Alaska, United States, 99508
Anchorage Oncology Centre, Anchorage, Alaska, United States, 99508
Katmai Oncology Group, Anchorage, Alaska, United States, 99508
Providence Alaska Medical Center, Anchorage, Alaska, United States, 99508
Kingman Regional Medical Center, Kingman, Arizona, United States, 86401
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
18 Years to
ALL
No
Alliance for Clinical Trials in Oncology,
Priscilla Brastianos, MD, STUDY_CHAIR, Massachusetts General Hospital
2028-01