RECRUITING

Use of CXCL9 as a Biomarker of Acthar Efficacy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective is this study is to test whether use of Acthar gel in the context of sarcoidosis will lead to improved symptoms and lung function and correlate with decreased levels of predictive blood biomarkers, like chemokine ligand 9 (CXCL9).

Official Title

Use of CXCL9 as a Biomarker of Acthar Efficacy

Quick Facts

Study Start:2022-11-03
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02523092

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Biopsy-proven diagnosis of sarcoidosis with demonstrated pulmonary involvement
  2. * Refractoriness to or intolerance of immunosuppressive agents like prednisone or methotrexate
  1. * Smoking
  2. * Cancer
  3. * Chronic infections (e.g. tuberculosis, viral, fungal, bacterial)
  4. * Inflammatory conditions
  5. * Coexisting lung disease
  6. * Congestive heart failure
  7. * Uncontrolled hypertension
  8. * Recent surgery
  9. * Active peptic ulcers
  10. * Osteoporosis

Contacts and Locations

Study Contact

Laura Koth, MD
CONTACT
(415) 514-4369
Laura.Koth@ucsf.edu

Principal Investigator

Laura Koth, MD
PRINCIPAL_INVESTIGATOR
University of California, San Francisco

Study Locations (Sites)

University of California, San Francisco
San Francisco, California, 94143
United States

Collaborators and Investigators

Sponsor: University of California, San Francisco

  • Laura Koth, MD, PRINCIPAL_INVESTIGATOR, University of California, San Francisco

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-11-03
Study Completion Date2026-12

Study Record Updates

Study Start Date2022-11-03
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • sarcoidosis
  • Acthar
  • CXCL9
  • chemokine ligand 9

Additional Relevant MeSH Terms

  • Sarcoidosis