Creatine for Depressed Male and Female Methamphetamine Users

Description

* Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users * Assess creatine's effect on methamphetamine use * Assess the safety of creatine in male methamphetamine users with depression

Conditions

Depression, Anxiety, Methamphetamine Dependence

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Study Overview

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Study Details

Study overview

* Assess the antidepressant/anxiolytic effect of creatine in male and female methamphetamine users * Assess creatine's effect on methamphetamine use * Assess the safety of creatine in male methamphetamine users with depression

An Open-Label Pilot Study of Creatine for Depressed Male and Female Methamphetamine Users

Creatine for Depressed Male and Female Methamphetamine Users

Condition
Depression
Intervention / Treatment

-

Contacts and Locations

Missoula

Montana State University College of Nursing (Missoula campus), Missoula, Montana, United States, 59812

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Current primary diagnosis of methamphetamine dependence or abuse, with methamphetamine preferred drug of abuse
  • * Current diagnosis of major depressive disorder (primary or substance-induced)
  • * Current diagnosis of an anxiety disorder (primary or substance-induced)
  • * Current Hamilton Depression Rating scale score \> or = to 16
  • * Current Hamilton Anxiety Scale score \> = to 18
  • * If taking a psychotropic medication for depressed or anxious mood, regimen must be stable for \> = to 4 weeks prior to creatine treatment initiation
  • * Persons unable to provide adequate informed consent
  • * Persons who are at clinically significant suicidal or homicidal risk
  • * Primary substance-related diagnosis other than methamphetamine dependence or abuse
  • * Positive pregnancy test (females only)
  • * History of renal disease
  • * Clinically significant medical or neurological illness identified by history, physical exam and laboratory testing
  • * History of hypersensitivity reaction to creatine

Ages Eligible for Study

18 Years to 59 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Montana State University,

Tracy Hellem, PhD, PRINCIPAL_INVESTIGATOR, Montana State University

Study Record Dates

2017-05