Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue

Description

This study will fill a scientific gap in the current knowledge providing data for evaluation of the palatal augmentation prosthesis (PAP) as a therapeutic modality post-surgery. This is a robust scientific randomized prospective clinical trial. Positive outcomes from this study have the potential to dramatically alter the most common issues of oral cancer therapy, namely speech and swallowing functions. Patients will have been diagnosed with a cancer lesion of the tongue requiring surgery and removal of part of the tongue. Smaller cancers of the tongue are sized as T1 or T2. For patients with smaller lesions, a PAP, which can aid in speaking and swallowing, is not routinely provided.

Conditions

Tongue Neoplasms, Tongue Cancer, Oral Cancer

Study Overview

Study Details

Study overview

This study will fill a scientific gap in the current knowledge providing data for evaluation of the palatal augmentation prosthesis (PAP) as a therapeutic modality post-surgery. This is a robust scientific randomized prospective clinical trial. Positive outcomes from this study have the potential to dramatically alter the most common issues of oral cancer therapy, namely speech and swallowing functions. Patients will have been diagnosed with a cancer lesion of the tongue requiring surgery and removal of part of the tongue. Smaller cancers of the tongue are sized as T1 or T2. For patients with smaller lesions, a PAP, which can aid in speaking and swallowing, is not routinely provided.

Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue (PGSRT): a Randomized Clinical Trial

Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue

Condition
Tongue Neoplasms
Intervention / Treatment

-

Contacts and Locations

Ann Arbor

University of Michigan Department of Oral and Maxillofacial Surgery and Hospital Dentistry, Ann Arbor, Michigan, United States, 48109

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with a new diagnosis of a T1/T2 tongue cancer
  • * Patients with recurrent disease
  • * Patients with a history of prior head and neck radiation therapy
  • * Patients who lack adequate maxillary dentition to support a palatal augmentation prosthesis

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Michigan,

Stephanie M Munz, DDS, PRINCIPAL_INVESTIGATOR, University of Michigan

Study Record Dates

2026-06