RECRUITING

Active Surveillance of Papillary Thyroid Microcarcinoma

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.

Official Title

Active Surveillance of Papillary Thyroid Microcarcinoma

Quick Facts

Study Start:2016-05-13
Study Completion:2030-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02609685

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Pathologically confirmed Bethesda V or VI thyroid nodules with papillary thyroid carcinoma or high clinical suspicion, or pathologically confirmed Bethesda III or IV nodules with BRAF mutation.
  2. * 2.0 cm or smaller nodules by ultrasonographic criteria
  3. * Ability to understand and the willingness to sign a written informed consent and HIPAA Authorization form
  4. * Must be able to read and write English fluently to participate in the questionnaire portion of the study
  1. * High-grade or poorly differentiated PTC variants
  2. * Central or lateral neck lymphadenopathy suspicious for PTC
  3. * Unfavorable nodule location (e.g. Near dorsal surface (by recurrent laryngeal nerve); Adjacent to trachea (risk of cartilage invasion)
  4. * History of radiation to neck

Contacts and Locations

Study Contact

Allen Ho, MD
CONTACT
310-423-1220
Allen.Ho@cshs.org

Principal Investigator

Allen Ho, MD
PRINCIPAL_INVESTIGATOR
Cedars-Sinal Medical Center

Study Locations (Sites)

Cedars-Sinai Medical Center
Los Angeles, California, 90048
United States

Collaborators and Investigators

Sponsor: Cedars-Sinai Medical Center

  • Allen Ho, MD, PRINCIPAL_INVESTIGATOR, Cedars-Sinal Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-05-13
Study Completion Date2030-12

Study Record Updates

Study Start Date2016-05-13
Study Completion Date2030-12

Terms related to this study

Keywords Provided by Researchers

  • Thyroid cancer
  • Active surveillance
  • PTMC

Additional Relevant MeSH Terms

  • Papillary Thyroid Microcarcinoma