Active Surveillance of Papillary Thyroid Microcarcinoma

Description

The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.

Conditions

Papillary Thyroid Microcarcinoma

Talk to us

Study Overview

On this page

Study Details

Study overview

The purpose of this study is to better understand the outcomes of active surveillance (observation) instead of immediate surgery, which is the current standard of care for papillary thyroid microcarcinoma (PTMC). Patients with a 1.5 cm or smaller thyroid nodule(s) with papillary thyroid carcinoma will be eligible for the study.

Active Surveillance of Papillary Thyroid Microcarcinoma

Active Surveillance of Papillary Thyroid Microcarcinoma

Condition
Papillary Thyroid Microcarcinoma
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Cedars-Sinai Medical Center, Los Angeles, California, United States, 90048

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Pathologically confirmed Bethesda V or VI thyroid nodules with papillary thyroid carcinoma or high clinical suspicion, or pathologically confirmed Bethesda III or IV nodules with BRAF mutation.
  • * 2.0 cm or smaller nodules by ultrasonographic criteria
  • * Ability to understand and the willingness to sign a written informed consent and HIPAA Authorization form
  • * Must be able to read and write English fluently to participate in the questionnaire portion of the study
  • * High-grade or poorly differentiated PTC variants
  • * Central or lateral neck lymphadenopathy suspicious for PTC
  • * Unfavorable nodule location (e.g. Near dorsal surface (by recurrent laryngeal nerve); Adjacent to trachea (risk of cartilage invasion)
  • * History of radiation to neck

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Cedars-Sinai Medical Center,

Allen Ho, MD, PRINCIPAL_INVESTIGATOR, Cedars-Sinal Medical Center

Study Record Dates

2030-12