RECRUITING

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

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Conditions

Head and Neck Squamous Cell CarcinomaHypopharyngeal Squamous Cell CarcinomaLaryngeal Squamous Cell CarcinomaLaryngeal Squamous Cell Carcinoma, Spindle Cell VariantLip and Oral Cavity Squamous Cell Carcinomap16INK4a Negative Oropharyngeal Squamous Cell CarcinomaStage III Hypopharyngeal Carcinoma AJCC v8Stage III Laryngeal Cancer AJCC v8Stage III Lip and Oral Cavity Cancer AJCC v8Stage III Oral Cavity Verrucous CarcinomaStage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8Stage IVA Hypopharyngeal Carcinoma AJCC v8Stage IVA Laryngeal Cancer AJCC v8Stage IVA Lip and Oral Cavity Cancer AJCC v8Stage IVA Oral Cavity Verrucous CarcinomaStage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This phase II trial studies how well radiation therapy with or without cisplatin works in treating patients with stage III-IVA squamous cell carcinoma of the head and neck who have undergone surgery. Radiation therapy uses high energy x-rays to kill tumor cells and shrink tumors. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. It is not yet known if radiation therapy is more effective with or without cisplatin in treating patients with squamous cell carcinoma of the head and neck.

Official Title

Phase II Randomized Trial of Radiotherapy With or Without Cisplatin for Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN) With TP53 Sequencing

Quick Facts

Study Start:2016-11-23
Study Completion:2027-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02734537

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * PRE-REGISTRATION (STEP 0)
  2. * Pathologically proven diagnosis of squamous cell carcinoma (including variants such as verrucous carcinoma, spindle cell carcinoma, carcinoma not otherwise specified \[NOS\]) of the head/neck (oral cavity, oropharynx, hypopharynx or larynx); pathologic stage III or IVA (American Joint Committee on Cancer \[AJCC\] 8): T3-T4a, N0-3, M0 or T1-T2, N1-3, M0
  3. * Patient has undergone total resection of the primary tumor with curative intent
  4. * NOTE: Patient is to be pre-registered to screening (Step 0) and tissue submitted to Foundation Medicine as soon as possible after surgery in order to meet the 8 week deadline to register the patient to Step 1 after surgery; full assay minimum turn-around time is 17-24 days
  5. * For oropharynx primary tumors, the patient must have negative human papillomavirus (HPV) status of the tumor as determined by p16 protein expression using immunohistochemistry (IHC)
  6. * Patients with, per the operative and/or pathology report, positive margin(s) (tumor present at the cut or inked edge of the tumor) which is not superceded by an additional margin of tumor-negative tissue, nodal extracapsular extension, and/or gross residual disease after surgery are not eligible
  7. * A paraffin-embedded surgical tumor tissue specimen has been located is available for shipment to Foundation Medicine, Inc. following pre-registration
  8. * NOTE: Complete the EA3132-specific FoundationOne requisition form
  9. * Patients with a history of a curatively treated malignancy must be disease-free for at least two years except for carcinoma in situ of cervix and/or non-melanomatous skin cancer; patients must not have received chemotherapy or investigational therapy within two years of surgical resection of the primary tumor
  10. * Patient must not have had previous irradiation to the head and neck that would result in overlap in radiation fields for the current disease
  11. * Patients with recurrent disease or multiple primaries are ineligible
  12. * RANDOMIZATION (STEP 1)
  13. * NOTE: Patient must meet all eligibility criteria outlined in pre-registration; patient may not be randomized until site has been notified that the central determination of p53 mutation status of the surgical tumor tissue has been completed and site has been notified of assay completion
  14. * Per the operative report, the gross total resection of the primary tumor with curative intent was completed within 8 weeks prior to randomization
  15. * The patient must have the following assessments done =\< 8 weeks prior to randomization:
  16. * Examination by a head and neck surgeon
  17. * Chest x-ray (or chest computed tomography \[CT\] scan or CT/positron emission tomography \[PET\] of the chest or magnetic resonance imaging \[MRI\]) to rule out distant metastatic disease
  18. * Patient has Eastern Cooperative Oncology Group (ECOG) performance status 0-1 within 2 weeks prior to randomization
  19. * Women must not be pregnant or breast-feeding; females of childbearing potential must have a blood or urine study within 2 weeks prior to randomization to rule out pregnancy; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has not undergone a hysterectomy or bilateral oophorectomy; or 2) has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
  20. * Women of childbearing potential and sexually active males must be strongly advised to use an accepted and effective method of contraception or to abstain from sexual intercourse for the duration of their participation in the study and until 60 days from the last study treatment
  21. * Absolute neutrophil count \>= 1,500/mm\^3 within 4 weeks prior to randomization
  22. * Platelets \>= 100,000/mm\^3 within 4 weeks prior to randomization
  23. * Total bilirubin =\< the upper limit of normal (ULN) within 4 weeks prior to randomization
  24. * Calculated creatinine clearance must be \> 60 ml/min using the Cockcroft-Gault formula within 4 weeks prior to randomization
  25. * Patient must not have an intercurrent illness likely to interfere with protocol therapy
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Robert Ferris
PRINCIPAL_INVESTIGATOR
ECOG-ACRIN Cancer Research Group

Study Locations (Sites)

University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, 35233
United States
Anchorage Associates in Radiation Medicine
Anchorage, Alaska, 98508
United States
Anchorage Radiation Therapy Center
Anchorage, Alaska, 99504
United States
Alaska Breast Care and Surgery LLC
Anchorage, Alaska, 99508
United States
Alaska Oncology and Hematology LLC
Anchorage, Alaska, 99508
United States
Alaska Women's Cancer Care
Anchorage, Alaska, 99508
United States
Anchorage Oncology Centre
Anchorage, Alaska, 99508
United States
Katmai Oncology Group
Anchorage, Alaska, 99508
United States
Providence Alaska Medical Center
Anchorage, Alaska, 99508
United States
Cancer Center at Saint Joseph's
Phoenix, Arizona, 85004
United States
University of Arizona Cancer Center-Orange Grove Campus
Tucson, Arizona, 85704
United States
Banner University Medical Center - Tucson
Tucson, Arizona, 85719
United States
University of Arizona Cancer Center-North Campus
Tucson, Arizona, 85719
United States
Mercy Hospital Fort Smith
Fort Smith, Arkansas, 72903
United States
CHI Saint Vincent Cancer Center Hot Springs
Hot Springs, Arkansas, 71913
United States
CARTI Cancer Center
Little Rock, Arkansas, 72205
United States
Mission Hope Medical Oncology - Arroyo Grande
Arroyo Grande, California, 93420
United States
Providence Saint Joseph Medical Center/Disney Family Cancer Center
Burbank, California, 91505
United States
Mercy Cancer Center - Carmichael
Carmichael, California, 95608
United States
Mercy San Juan Medical Center
Carmichael, California, 95608
United States
Mercy Cancer Center - Elk Grove
Elk Grove, California, 95758
United States
UC San Diego Moores Cancer Center
La Jolla, California, 92093
United States
Mercy Cancer Center
Merced, California, 95340
United States
Desert Regional Medical Center
Palm Springs, California, 92262
United States
Mercy Cancer Center - Rocklin
Rocklin, California, 95765
United States
Mercy Cancer Center - Sacramento
Sacramento, California, 95816
United States
Pacific Central Coast Health Center-San Luis Obispo
San Luis Obispo, California, 93401
United States
Mission Hope Medical Oncology - Santa Maria
Santa Maria, California, 93444
United States
Woodland Memorial Hospital
Woodland, California, 95695
United States
Penrose-Saint Francis Healthcare
Colorado Springs, Colorado, 80907
United States
Rocky Mountain Cancer Centers-Penrose
Colorado Springs, Colorado, 80907
United States
Saint Francis Cancer Center
Colorado Springs, Colorado, 80923
United States
Porter Adventist Hospital
Denver, Colorado, 80210
United States
Mercy Medical Center
Durango, Colorado, 81301
United States
Southwest Oncology PC
Durango, Colorado, 81301
United States
Mountain Blue Cancer Care Center
Golden, Colorado, 80401
United States
Rocky Mountain Cancer Centers-Lakewood
Lakewood, Colorado, 80228
United States
Saint Anthony Hospital
Lakewood, Colorado, 80228
United States
Littleton Adventist Hospital
Littleton, Colorado, 80122
United States
Longmont United Hospital
Longmont, Colorado, 80501
United States
Rocky Mountain Cancer Centers-Longmont
Longmont, Colorado, 80501
United States
Parker Adventist Hospital
Parker, Colorado, 80138
United States
Rocky Mountain Cancer Centers-Parker
Parker, Colorado, 80138
United States
Saint Mary Corwin Medical Center
Pueblo, Colorado, 81004
United States
Rocky Mountain Cancer Centers - Pueblo
Pueblo, Colorado, 81008
United States
Rocky Mountain Cancer Centers-Thornton
Thornton, Colorado, 80260
United States
Smilow Cancer Hospital Care Center at Greenwich
Greenwich, Connecticut, 06830
United States
Smilow Cancer Hospital Care Center - Guilford
Guilford, Connecticut, 06437
United States
Middlesex Hospital
Middletown, Connecticut, 06457
United States
Smilow Cancer Center/Yale-New Haven Hospital
New Haven, Connecticut, 06510
United States
Yale University
New Haven, Connecticut, 06520
United States
Yale-New Haven Hospital North Haven Medical Center
North Haven, Connecticut, 06473
United States
Smilow Cancer Hospital Care Center-Trumbull
Trumbull, Connecticut, 06611
United States
Smilow Cancer Hospital Care Center - Waterford
Waterford, Connecticut, 06385
United States
Beebe Medical Center
Lewes, Delaware, 19958
United States
Delaware Clinical and Laboratory Physicians PA
Newark, Delaware, 19713
United States
Helen F Graham Cancer Center
Newark, Delaware, 19713
United States
Medical Oncology Hematology Consultants PA
Newark, Delaware, 19713
United States
Christiana Care Health System-Christiana Hospital
Newark, Delaware, 19718
United States
Beebe Health Campus
Rehoboth Beach, Delaware, 19971
United States
TidalHealth Nanticoke / Allen Cancer Center
Seaford, Delaware, 19973
United States
Christiana Care Health System-Wilmington Hospital
Wilmington, Delaware, 19801
United States
Sibley Memorial Hospital
Washington, District of Columbia, 20016
United States
George Washington University Medical Center
Washington, District of Columbia, 20037
United States
UM Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, 33146
United States
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, 33442
United States
Holy Cross Hospital
Fort Lauderdale, Florida, 33308
United States
University of Florida Health Science Center - Gainesville
Gainesville, Florida, 32610
United States
Baptist MD Anderson Cancer Center
Jacksonville, Florida, 32207
United States
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, 33136
United States
UM Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, 33324
United States
Moffitt Cancer Center-International Plaza
Tampa, Florida, 33607
United States
Moffitt Cancer Center - McKinley Campus
Tampa, Florida, 33612
United States
Moffitt Cancer Center
Tampa, Florida, 33612
United States
Emory University Hospital Midtown
Atlanta, Georgia, 30308
United States
Emory University Hospital/Winship Cancer Institute
Atlanta, Georgia, 30322
United States
Hawaii Cancer Care - Westridge
'Aiea, Hawaii, 96701
United States
Pali Momi Medical Center
'Aiea, Hawaii, 96701
United States
Queen's Cancer Center - Pearlridge
'Aiea, Hawaii, 96701
United States
The Cancer Center of Hawaii-Pali Momi
'Aiea, Hawaii, 96701
United States
Hawaii Cancer Care Inc - Waterfront Plaza
Honolulu, Hawaii, 96813
United States
Island Urology
Honolulu, Hawaii, 96813
United States
Queen's Cancer Cenrer - POB I
Honolulu, Hawaii, 96813
United States
Queen's Medical Center
Honolulu, Hawaii, 96813
United States
Straub Clinic and Hospital
Honolulu, Hawaii, 96813
United States
University of Hawaii Cancer Center
Honolulu, Hawaii, 96813
United States
Hawaii Cancer Care Inc-Liliha
Honolulu, Hawaii, 96817
United States
Kuakini Medical Center
Honolulu, Hawaii, 96817
United States
Queen's Cancer Center - Kuakini
Honolulu, Hawaii, 96817
United States
The Cancer Center of Hawaii-Liliha
Honolulu, Hawaii, 96817
United States
Kapiolani Medical Center for Women and Children
Honolulu, Hawaii, 96826
United States
Wilcox Memorial Hospital and Kauai Medical Clinic
Lihue, Hawaii, 96766
United States
Saint Alphonsus Cancer Care Center-Boise
Boise, Idaho, 83706
United States
Saint Luke's Cancer Institute - Boise
Boise, Idaho, 83712
United States
Saint Alphonsus Cancer Care Center-Caldwell
Caldwell, Idaho, 83605
United States
Kootenai Health - Coeur d'Alene
Coeur d'Alene, Idaho, 83814
United States
Walter Knox Memorial Hospital
Emmett, Idaho, 83617
United States
Saint Luke's Cancer Institute - Fruitland
Fruitland, Idaho, 83619
United States
Idaho Urologic Institute-Meridian
Meridian, Idaho, 83642
United States
Saint Luke's Cancer Institute - Meridian
Meridian, Idaho, 83642
United States
Saint Luke's Cancer Institute - Nampa
Nampa, Idaho, 83686
United States
Saint Alphonsus Cancer Care Center-Nampa
Nampa, Idaho, 83687
United States
Kootenai Clinic Cancer Services - Post Falls
Post Falls, Idaho, 83854
United States
Kootenai Clinic Cancer Services - Sandpoint
Sandpoint, Idaho, 83864
United States
Saint Luke's Cancer Institute - Twin Falls
Twin Falls, Idaho, 83301
United States
Saint Anthony's Health
Alton, Illinois, 62002
United States
Rush - Copley Medical Center
Aurora, Illinois, 60504
United States
Advocate Good Shepherd Hospital
Barrington, Illinois, 60010
United States
OSF Saint Joseph Medical Center
Bloomington, Illinois, 61701
United States
Illinois CancerCare-Bloomington
Bloomington, Illinois, 61704
United States
Illinois CancerCare-Canton
Canton, Illinois, 61520
United States
Memorial Hospital of Carbondale
Carbondale, Illinois, 62902
United States
SIH Cancer Institute
Carterville, Illinois, 62918
United States
Illinois CancerCare-Carthage
Carthage, Illinois, 62321
United States
Centralia Oncology Clinic
Centralia, Illinois, 62801
United States
Saint Mary's Hospital
Centralia, Illinois, 62801
United States
Northwestern University
Chicago, Illinois, 60611
United States
John H Stroger Jr Hospital of Cook County
Chicago, Illinois, 60612
United States
University of Illinois
Chicago, Illinois, 60612
United States
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, 60637
United States
Advocate Illinois Masonic Medical Center
Chicago, Illinois, 60657
United States
AMG Crystal Lake - Oncology
Crystal Lake, Illinois, 60014
United States
Carle at The Riverfront
Danville, Illinois, 61832
United States
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, 62526
United States
Decatur Memorial Hospital
Decatur, Illinois, 62526
United States
Illinois CancerCare-Dixon
Dixon, Illinois, 61021
United States
Advocate Good Samaritan Hospital
Downers Grove, Illinois, 60515
United States
Carle Physician Group-Effingham
Effingham, Illinois, 62401
United States
Crossroads Cancer Center
Effingham, Illinois, 62401
United States
Advocate Sherman Hospital
Elgin, Illinois, 60123
United States
Illinois CancerCare-Eureka
Eureka, Illinois, 61530
United States
NorthShore University HealthSystem-Evanston Hospital
Evanston, Illinois, 60201
United States
Illinois CancerCare-Galesburg
Galesburg, Illinois, 61401
United States
Western Illinois Cancer Treatment Center
Galesburg, Illinois, 61401
United States
NorthShore University HealthSystem-Glenbrook Hospital
Glenview, Illinois, 60026
United States
Advocate South Suburban Hospital
Hazel Crest, Illinois, 60429
United States
NorthShore University HealthSystem-Highland Park Hospital
Highland Park, Illinois, 60035
United States
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, 61443
United States
AMG Libertyville - Oncology
Libertyville, Illinois, 60048
United States
Condell Memorial Hospital
Libertyville, Illinois, 60048
United States
Illinois CancerCare-Macomb
Macomb, Illinois, 61455
United States
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, 61938
United States
Good Samaritan Regional Health Center
Mount Vernon, Illinois, 62864
United States
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, 60451
United States
Cancer Care Center of O'Fallon
O'Fallon, Illinois, 62269
United States
HSHS Saint Elizabeth's Hospital
O'Fallon, Illinois, 62269
United States
Advocate Christ Medical Center
Oak Lawn, Illinois, 60453-2699
United States
Advocate Outpatient Center - Oak Lawn
Oak Lawn, Illinois, 60453
United States
University of Chicago Medicine-Orland Park
Orland Park, Illinois, 60462
United States
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, 61350
United States
Radiation Oncology of Northern Illinois
Ottawa, Illinois, 61350
United States
Advocate High Tech Medical Park
Palos Heights, Illinois, 60463
United States
Advocate Lutheran General Hospital
Park Ridge, Illinois, 60068
United States
Illinois CancerCare-Pekin
Pekin, Illinois, 61554
United States
OSF Saint Francis Radiation Oncology at Pekin
Pekin, Illinois, 61554
United States
Illinois CancerCare-Peoria
Peoria, Illinois, 61615
United States
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Peoria, Illinois, 61615
United States
Methodist Medical Center of Illinois
Peoria, Illinois, 61636
United States
OSF Saint Francis Medical Center
Peoria, Illinois, 61637
United States
Illinois CancerCare-Peru
Peru, Illinois, 61354
United States
Valley Radiation Oncology
Peru, Illinois, 61354
United States
Illinois CancerCare-Princeton
Princeton, Illinois, 61356
United States
UW Health Carbone Cancer Center Rockford
Rockford, Illinois, 61114
United States
North Shore Medical Center
Skokie, Illinois, 60076
United States
Central Illinois Hematology Oncology Center
Springfield, Illinois, 62702
United States
Southern Illinois University School of Medicine
Springfield, Illinois, 62702
United States
Springfield Clinic
Springfield, Illinois, 62702
United States
Memorial Medical Center
Springfield, Illinois, 62781
United States
Southwest Illinois Health Services LLP
Swansea, Illinois, 62226
United States
Carle Cancer Center
Urbana, Illinois, 61801
United States
The Carle Foundation Hospital
Urbana, Illinois, 61801
United States
Illinois CancerCare - Washington
Washington, Illinois, 61571
United States
Rush-Copley Healthcare Center
Yorkville, Illinois, 60560
United States
IU Health North Hospital
Carmel, Indiana, 46032
United States
Indiana University/Melvin and Bren Simon Cancer Center
Indianapolis, Indiana, 46202
United States
IU Health Methodist Hospital
Indianapolis, Indiana, 46202
United States
Sidney and Lois Eskenazi Hospital
Indianapolis, Indiana, 46202
United States
Community Cancer Center East
Indianapolis, Indiana, 46219
United States
Community Cancer Center South
Indianapolis, Indiana, 46227
United States
Community Cancer Center North
Indianapolis, Indiana, 46256
United States
Community Howard Regional Health
Kokomo, Indiana, 46904
United States
Reid Health
Richmond, Indiana, 47374
United States
Mission Cancer and Blood - Ankeny
Ankeny, Iowa, 50023
United States
Mercy Cancer Center-West Lakes
Clive, Iowa, 50325
United States
Mission Cancer and Blood - West Des Moines
Clive, Iowa, 50325
United States
Alegent Health Mercy Hospital
Council Bluffs, Iowa, 51503
United States
Heartland Oncology and Hematology LLP
Council Bluffs, Iowa, 51503
United States
Methodist Jennie Edmundson Hospital
Council Bluffs, Iowa, 51503
United States
Greater Regional Medical Center
Creston, Iowa, 50801
United States
Mercy Medical Center - Des Moines
Des Moines, Iowa, 50314
United States
Mission Cancer and Blood - Laurel
Des Moines, Iowa, 50314
United States
Mercy Medical Center-West Lakes
West Des Moines, Iowa, 50266
United States
Central Care Cancer Center - Garden City
Garden City, Kansas, 67846
United States
Central Care Cancer Center - Great Bend
Great Bend, Kansas, 67530
United States
Flaget Memorial Hospital
Bardstown, Kentucky, 40004
United States
Commonwealth Cancer Center-Corbin
Corbin, Kentucky, 40701
United States
Oncology Hematology Care Inc-Crestview
Crestview Hills, Kentucky, 41017
United States
Saint Joseph Hospital
Lexington, Kentucky, 40504
United States
Saint Joseph Radiation Oncology Resource Center
Lexington, Kentucky, 40504
United States
Saint Joseph Hospital East
Lexington, Kentucky, 40509
United States
Saint Joseph London
London, Kentucky, 40741
United States
Jewish Hospital
Louisville, Kentucky, 40202
United States
The James Graham Brown Cancer Center at University of Louisville
Louisville, Kentucky, 40202
United States
Saints Mary and Elizabeth Hospital
Louisville, Kentucky, 40215
United States
UofL Health Medical Center Northeast
Louisville, Kentucky, 40245
United States
Saint Joseph Mount Sterling
Mount Sterling, Kentucky, 40353
United States
Jewish Hospital Medical Center South
Shepherdsville, Kentucky, 40165
United States
Louisiana State University Health Science Center
New Orleans, Louisiana, 70112
United States
University Medical Center New Orleans
New Orleans, Louisiana, 70112
United States
University of Maryland/Greenebaum Cancer Center
Baltimore, Maryland, 21201
United States
Greater Baltimore Medical Center
Baltimore, Maryland, 21204
United States
Johns Hopkins University/Sidney Kimmel Cancer Center
Baltimore, Maryland, 21287
United States
UM Upper Chesapeake Medical Center
Bel Air, Maryland, 21014
United States
Suburban Hospital
Bethesda, Maryland, 20814
United States
Central Maryland Radiation Oncology in Howard County
Columbia, Maryland, 21044
United States
UM Baltimore Washington Medical Center/Tate Cancer Center
Glen Burnie, Maryland, 21061
United States
Tufts Medical Center
Boston, Massachusetts, 02111
United States
Mercy Medical Center
Springfield, Massachusetts, 01104
United States
Trinity Health Saint Joseph Mercy Hospital Ann Arbor
Ann Arbor, Michigan, 48106
United States
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109
United States
Bronson Battle Creek
Battle Creek, Michigan, 49017
United States
Trinity Health IHA Medical Group Hematology Oncology - Brighton
Brighton, Michigan, 48114
United States
Trinity Health Medical Center - Brighton
Brighton, Michigan, 48114
United States
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, 48116
United States
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, 48183
United States
Trinity Health IHA Medical Group Hematology Oncology - Canton
Canton, Michigan, 48188
United States
Trinity Health Medical Center - Canton
Canton, Michigan, 48188
United States
Caro Cancer Center
Caro, Michigan, 48723
United States
Chelsea Hospital
Chelsea, Michigan, 48118
United States
Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital
Chelsea, Michigan, 48118
United States
Hematology Oncology Consultants-Clarkston
Clarkston, Michigan, 48346
United States
Newland Medical Associates-Clarkston
Clarkston, Michigan, 48346
United States
Henry Ford Hematology Oncology - Hayes
Clinton Township, Michigan, 48038
United States
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, 48038
United States
Corewell Health Dearborn Hospital
Dearborn, Michigan, 48124
United States
Henry Ford Medical Center-Fairlane
Dearborn, Michigan, 48126
United States
Wayne State University/Karmanos Cancer Institute
Detroit, Michigan, 48201
United States
Henry Ford Hospital
Detroit, Michigan, 48202
United States
Ascension Saint John Hospital
Detroit, Michigan, 48236
United States
Great Lakes Cancer Management Specialists-Doctors Park
East China Township, Michigan, 48054
United States
Weisberg Cancer Treatment Center
Farmington Hills, Michigan, 48334
United States
Genesee Cancer and Blood Disease Treatment Center
Flint, Michigan, 48503
United States
Genesee Hematology Oncology PC
Flint, Michigan, 48503
United States
Genesys Hurley Cancer Institute
Flint, Michigan, 48503
United States
Hurley Medical Center
Flint, Michigan, 48503
United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
Grand Rapids, Michigan, 49503
United States
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503
United States
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, 49503
United States
Academic Hematology Oncology Specialists
Grosse Pointe Woods, Michigan, 48236
United States
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Grosse Pointe Woods, Michigan, 48236
United States
Michigan Breast Specialists-Grosse Pointe Woods
Grosse Pointe Woods, Michigan, 48236
United States
Allegiance Health
Jackson, Michigan, 49201
United States
Bronson Methodist Hospital
Kalamazoo, Michigan, 49007
United States
West Michigan Cancer Center
Kalamazoo, Michigan, 49007
United States
Ascension Borgess Cancer Center
Kalamazoo, Michigan, 49009
United States
Borgess Medical Center
Kalamazoo, Michigan, 49048
United States
University of Michigan Health - Sparrow Lansing
Lansing, Michigan, 48912
United States
Hope Cancer Clinic
Livonia, Michigan, 48154
United States
Trinity Health Saint Mary Mercy Livonia Hospital
Livonia, Michigan, 48154
United States
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Macomb, Michigan, 48044
United States
Michigan Breast Specialists-Macomb Township
Macomb, Michigan, 48044
United States
Saint Mary's Oncology/Hematology Associates of Marlette
Marlette, Michigan, 48453
United States
Trinity Health Muskegon Hospital
Muskegon, Michigan, 49444
United States
Corewell Health Lakeland Hospitals - Niles Hospital
Niles, Michigan, 49120
United States
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan, 49444
United States
Henry Ford Medical Center-Columbus
Novi, Michigan, 48377
United States
Hope Cancer Center
Pontiac, Michigan, 48341
United States
Michigan Healthcare Professionals Pontiac
Pontiac, Michigan, 48341
United States
Newland Medical Associates-Pontiac
Pontiac, Michigan, 48341
United States
Trinity Health Saint Joseph Mercy Oakland Hospital
Pontiac, Michigan, 48341
United States
Corewell Health Reed City Hospital
Reed City, Michigan, 49677
United States
Great Lakes Cancer Management Specialists-Rochester Hills
Rochester Hills, Michigan, 48309
United States
Ascension Saint Mary's Hospital
Saginaw, Michigan, 48601
United States
Oncology Hematology Associates of Saginaw Valley PC
Saginaw, Michigan, 48604
United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
Saint Joseph, Michigan, 49085
United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital
Saint Joseph, Michigan, 49085
United States
Henry Ford Macomb Health Center - Shelby Township
Shelby, Michigan, 48315
United States
Bhadresh Nayak MD PC-Sterling Heights
Sterling Heights, Michigan, 48312
United States
Ascension Saint Joseph Hospital
Tawas City, Michigan, 48764
United States
Munson Medical Center
Traverse City, Michigan, 49684
United States
Advanced Breast Care Center PLLC
Warren, Michigan, 48088
United States
Great Lakes Cancer Management Specialists-Macomb Professional Building
Warren, Michigan, 48093
United States
Macomb Hematology Oncology PC
Warren, Michigan, 48093
United States
Michigan Breast Specialists-Warren
Warren, Michigan, 48093
United States
Saint John Macomb-Oakland Hospital
Warren, Michigan, 48093
United States
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, 48322
United States
Saint Mary's Oncology/Hematology Associates of West Branch
West Branch, Michigan, 48661
United States
Henry Ford Wyandotte Hospital
Wyandotte, Michigan, 48192
United States
University of Michigan Health - West
Wyoming, Michigan, 49519
United States
Huron Gastroenterology PC
Ypsilanti, Michigan, 48106
United States
Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus
Ypsilanti, Michigan, 48197
United States
Riverwood Healthcare Center
Aitkin, Minnesota, 56431
United States
Mayo Clinic Health System in Albert Lea
Albert Lea, Minnesota, 56007
United States
Essentia Health - Baxter Clinic
Baxter, Minnesota, 56425
United States
Sanford Joe Lueken Cancer Center
Bemidji, Minnesota, 56601
United States
Essentia Health Saint Joseph's Medical Center
Brainerd, Minnesota, 56401
United States
Fairview Ridges Hospital
Burnsville, Minnesota, 55337
United States
Minnesota Oncology - Burnsville
Burnsville, Minnesota, 55337
United States
Cambridge Medical Center
Cambridge, Minnesota, 55008
United States
Mercy Hospital
Coon Rapids, Minnesota, 55433
United States
Essentia Health - Deer River Clinic
Deer River, Minnesota, 56636
United States
Essentia Health Saint Mary's - Detroit Lakes Clinic
Detroit Lakes, Minnesota, 56501
United States
Essentia Health Cancer Center
Duluth, Minnesota, 55805
United States
Essentia Health Saint Mary's Medical Center
Duluth, Minnesota, 55805
United States
Miller-Dwan Hospital
Duluth, Minnesota, 55805
United States
Fairview Southdale Hospital
Edina, Minnesota, 55435
United States
Essentia Health - Ely Clinic
Ely, Minnesota, 55731
United States
Lake Region Healthcare Corporation-Cancer Care
Fergus Falls, Minnesota, 56537
United States
Essentia Health - Fosston
Fosston, Minnesota, 56542
United States
Unity Hospital
Fridley, Minnesota, 55432
United States
Essentia Health Hibbing Clinic
Hibbing, Minnesota, 55746
United States
Essentia Health - International Falls Clinic
International Falls, Minnesota, 56649
United States
Mayo Clinic Health Systems-Mankato
Mankato, Minnesota, 56001
United States
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, 55369
United States
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, 55109
United States
Saint John's Hospital - Healtheast
Maplewood, Minnesota, 55109
United States
Abbott-Northwestern Hospital
Minneapolis, Minnesota, 55407
United States
Hennepin County Medical Center
Minneapolis, Minnesota, 55415
United States
Health Partners Inc
Minneapolis, Minnesota, 55454
United States
Monticello Cancer Center
Monticello, Minnesota, 55362
United States
Essentia Health - Moose Lake Clinic
Moose Lake, Minnesota, 55767
United States
New Ulm Medical Center
New Ulm, Minnesota, 56073
United States
Mayo Clinic Radiation Therapy-Northfield
Northfield, Minnesota, 55057
United States
Essentia Health - Park Rapids
Park Rapids, Minnesota, 56470
United States
Fairview Northland Medical Center
Princeton, Minnesota, 55371
United States
North Memorial Medical Health Center
Robbinsdale, Minnesota, 55422
United States
Mayo Clinic in Rochester
Rochester, Minnesota, 55905
United States
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, 56303
United States
Saint Cloud Hospital
Saint Cloud, Minnesota, 56303
United States
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, 55416
United States
Regions Hospital
Saint Paul, Minnesota, 55101
United States
United Hospital
Saint Paul, Minnesota, 55102
United States
Essentia Health Sandstone
Sandstone, Minnesota, 55072
United States
Saint Francis Regional Medical Center
Shakopee, Minnesota, 55379
United States
Lakeview Hospital
Stillwater, Minnesota, 55082
United States
Sanford Thief River Falls Medical Center
Thief River Falls, Minnesota, 56701
United States
Essentia Health Virginia Clinic
Virginia, Minnesota, 55792
United States
Ridgeview Medical Center
Waconia, Minnesota, 55387
United States
Rice Memorial Hospital
Willmar, Minnesota, 56201
United States
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, 55125
United States
Sanford Cancer Center Worthington
Worthington, Minnesota, 56187
United States
Fairview Lakes Medical Center
Wyoming, Minnesota, 55092
United States
University of Mississippi Medical Center
Jackson, Mississippi, 39216
United States
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri, 63011
United States
Central Care Cancer Center - Bolivar
Bolivar, Missouri, 65613
United States
Parkland Health Center-Bonne Terre
Bonne Terre, Missouri, 63628
United States
Cox Cancer Center Branson
Branson, Missouri, 65616
United States
Saint Francis Medical Center
Cape Girardeau, Missouri, 63703
United States
Southeast Cancer Center
Cape Girardeau, Missouri, 63703
United States
Parkland Health Center - Farmington
Farmington, Missouri, 63640
United States
MU Health Care Goldschmidt Cancer Center
Jefferson City, Missouri, 65109
United States
Freeman Health System
Joplin, Missouri, 64804
United States
Mercy Hospital Joplin
Joplin, Missouri, 64804
United States
Lake Regional Hospital
Osage Beach, Missouri, 65065
United States
Delbert Day Cancer Institute at PCRMC
Rolla, Missouri, 65401
United States
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, 65401
United States
Heartland Regional Medical Center
Saint Joseph, Missouri, 64506
United States
Saint Louis Cancer and Breast Institute-South City
Saint Louis, Missouri, 63109
United States
Mercy Hospital South
Saint Louis, Missouri, 63128
United States
Missouri Baptist Medical Center
Saint Louis, Missouri, 63131
United States
Mercy Hospital Saint Louis
Saint Louis, Missouri, 63141
United States
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, 63670
United States
Mercy Hospital Springfield
Springfield, Missouri, 65804
United States
CoxHealth South Hospital
Springfield, Missouri, 65807
United States
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, 63080
United States
BJC Outpatient Center at Sunset Hills
Sunset Hills, Missouri, 63127
United States
Mercy Hospital Washington
Washington, Missouri, 63090
United States
Community Hospital of Anaconda
Anaconda, Montana, 59711
United States
Billings Clinic Cancer Center
Billings, Montana, 59101
United States
Saint Vincent Healthcare
Billings, Montana, 59101
United States
Bozeman Health Deaconess Hospital
Bozeman, Montana, 59715
United States
Saint James Community Hospital and Cancer Treatment Center
Butte, Montana, 59701
United States
Benefis Sletten Cancer Institute
Great Falls, Montana, 59405
United States
Great Falls Clinic
Great Falls, Montana, 59405
United States
Saint Peter's Community Hospital
Helena, Montana, 59601
United States
Kalispell Regional Medical Center
Kalispell, Montana, 59901
United States
Saint Patrick Hospital - Community Hospital
Missoula, Montana, 59802
United States
Community Medical Center
Missoula, Montana, 59804
United States
Nebraska Cancer Specialists/Oncology Hematology West PC
Grand Island, Nebraska, 68803
United States
Heartland Hematology and Oncology
Kearney, Nebraska, 68845
United States
CHI Health Good Samaritan
Kearney, Nebraska, 68847
United States
Nebraska Hematology and Oncology
Lincoln, Nebraska, 68506
United States
Nebraska Cancer Research Center
Lincoln, Nebraska, 68510
United States
Saint Elizabeth Regional Medical Center
Lincoln, Nebraska, 68510
United States
Cancer Partners of Nebraska
Lincoln, Nebraska, 68516
United States
Faith Regional Health Services Carson Cancer Center
Norfolk, Nebraska, 68701
United States
Great Plains Health Callahan Cancer Center
North Platte, Nebraska, 69101
United States
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha, Nebraska, 68114
United States
Nebraska Methodist Hospital
Omaha, Nebraska, 68114
United States
Oncology Associates PC
Omaha, Nebraska, 68114
United States
Alegent Health Immanuel Medical Center
Omaha, Nebraska, 68122
United States
Hematology and Oncology Consultants PC
Omaha, Nebraska, 68122
United States
Alegent Health Bergan Mercy Medical Center
Omaha, Nebraska, 68124
United States
Nebraska Cancer Specialists - Omaha
Omaha, Nebraska, 68124
United States
Alegent Health Lakeside Hospital
Omaha, Nebraska, 68130
United States
Oncology Hematology West PC
Omaha, Nebraska, 68130
United States
Creighton University Medical Center
Omaha, Nebraska, 68131
United States
Midlands Community Hospital
Papillion, Nebraska, 68046
United States
Regional West Medical Center Cancer Center
Scottsbluff, Nebraska, 69361
United States
Jersey City Medical Center
Jersey City, New Jersey, 07302
United States
Monmouth Medical Center
Long Branch, New Jersey, 07740
United States
Morristown Medical Center
Morristown, New Jersey, 07960
United States
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08903
United States
Rutgers New Jersey Medical School
Newark, New Jersey, 07101
United States
Sparta Cancer Treatment Center
Sparta, New Jersey, 07871
United States
Overlook Hospital
Summit, New Jersey, 07902
United States
Community Medical Center
Toms River, New Jersey, 08755
United States
University of New Mexico Cancer Center
Albuquerque, New Mexico, 87106
United States
New Mexico Oncology Hematology Consultants
Albuquerque, New Mexico, 87109
United States
Memorial Medical Center - Las Cruces
Las Cruces, New Mexico, 88011
United States
Northwell Health Imbert Cancer Center
Bay Shore, New York, 11706
United States
Montefiore Medical Center-Einstein Campus
Bronx, New York, 10461
United States
Montefiore Medical Center-Weiler Hospital
Bronx, New York, 10461
United States
Montefiore Medical Center - Moses Campus
Bronx, New York, 10467
United States
Roswell Park Cancer Institute
Buffalo, New York, 14263
United States
Northwell Health/Center for Advanced Medicine
Lake Success, New York, 11042
United States
Garnet Health Medical Center
Middletown, New York, 10940
United States
Long Island Jewish Medical Center
New Hyde Park, New York, 11040
United States
Lenox Hill Hospital
New York, New York, 10021
United States
Manhattan Eye Ear and Throat Hospital
New York, New York, 10065
United States
Highland Hospital
Rochester, New York, 14620
United States
University of Rochester
Rochester, New York, 14642
United States
Stony Brook University Medical Center
Stony Brook, New York, 11794
United States
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina, 28328
United States
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina, 27534
United States
Wayne Memorial Hospital
Goldsboro, North Carolina, 27534
United States
Onslow Memorial Hospital
Jacksonville, North Carolina, 28546
United States
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina, 28546
United States
Sanford Bismarck Medical Center
Bismarck, North Dakota, 58501
United States
Essentia Health Cancer Center-South University Clinic
Fargo, North Dakota, 58103
United States
Sanford South University Medical Center
Fargo, North Dakota, 58103
United States
Sanford Broadway Medical Center
Fargo, North Dakota, 58122
United States
Sanford Roger Maris Cancer Center
Fargo, North Dakota, 58122
United States
Essentia Health - Jamestown Clinic
Jamestown, North Dakota, 58401
United States
UH Seidman Cancer Center at UH Avon Health Center
Avon, Ohio, 44011
United States
Indu and Raj Soin Medical Center
Beavercreek, Ohio, 45431
United States
Saint Elizabeth Boardman Hospital
Boardman, Ohio, 44512
United States
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, 45459
United States
Miami Valley Hospital South
Centerville, Ohio, 45459
United States
Geauga Hospital
Chardon, Ohio, 44024
United States
Oncology Hematology Care Inc-Eden Park
Cincinnati, Ohio, 45202
United States
Oncology Hematology Care Inc-Mercy West
Cincinnati, Ohio, 45211
United States
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, 45219
United States
Good Samaritan Hospital - Cincinnati
Cincinnati, Ohio, 45220
United States
Oncology Hematology Care Inc-Anderson
Cincinnati, Ohio, 45230
United States
Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio, 45236
United States
Bethesda North Hospital
Cincinnati, Ohio, 45242
United States
Oncology Hematology Care Inc-Blue Ash
Cincinnati, Ohio, 45242
United States
TriHealth Cancer Institute-Westside
Cincinnati, Ohio, 45247
United States
TriHealth Cancer Institute-Anderson
Cincinnati, Ohio, 45255
United States
Case Western Reserve University
Cleveland, Ohio, 44106
United States
Cleveland Clinic Foundation
Cleveland, Ohio, 44195
United States
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, 43210
United States
Good Samaritan Hospital - Dayton
Dayton, Ohio, 45406
United States
Miami Valley Hospital
Dayton, Ohio, 45409
United States
Dayton Physician LLC - Englewood
Dayton, Ohio, 45415
United States
Miami Valley Hospital North
Dayton, Ohio, 45415
United States
Mercy Cancer Center-Elyria
Elyria, Ohio, 44035
United States
Oncology Hematology Care Inc-Healthplex
Fairfield, Ohio, 45014
United States
Armes Family Cancer Center
Findlay, Ohio, 45840
United States
Blanchard Valley Hospital
Findlay, Ohio, 45840
United States
Orion Cancer Care
Findlay, Ohio, 45840
United States
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, 45005-1066
United States
Dayton Physicians LLC-Atrium
Franklin, Ohio, 45005
United States
Dayton Physicians LLC-Wayne
Greenville, Ohio, 45331
United States
Wayne Hospital
Greenville, Ohio, 45331
United States
Greater Dayton Cancer Center
Kettering, Ohio, 45409
United States
First Dayton Cancer Care
Kettering, Ohio, 45420
United States
Kettering Medical Center
Kettering, Ohio, 45429
United States
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio, 44060
United States
Dayton Physicians LLC-Signal Point
Middletown, Ohio, 45042
United States
Dayton Physicians LLC-Wilson
Sidney, Ohio, 45365
United States
Springfield Regional Cancer Center
Springfield, Ohio, 45504
United States
Springfield Regional Medical Center
Springfield, Ohio, 45504
United States
Dayton Physicians LLC - Troy
Troy, Ohio, 45373
United States
Upper Valley Medical Center
Troy, Ohio, 45373
United States
Saint Joseph Warren Hospital
Warren, Ohio, 44484
United States
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, 45069
United States
UH Seidman Cancer Center at Saint John Medical Center
Westlake, Ohio, 44145
United States
UHHS-Westlake Medical Center
Westlake, Ohio, 44145
United States
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio, 44501
United States
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, 73104
United States
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, 73120
United States
Saint Alphonsus Cancer Care Center-Baker City
Baker City, Oregon, 97814
United States
Saint Charles Health System
Bend, Oregon, 97701
United States
Clackamas Radiation Oncology Center
Clackamas, Oregon, 97015
United States
Providence Cancer Institute Clackamas Clinic
Clackamas, Oregon, 97015
United States
Bay Area Hospital
Coos Bay, Oregon, 97420
United States
Legacy Mount Hood Medical Center
Gresham, Oregon, 97030
United States
Providence Newberg Medical Center
Newberg, Oregon, 97132
United States
Saint Alphonsus Cancer Care Center-Ontario
Ontario, Oregon, 97914
United States
Providence Willamette Falls Medical Center
Oregon City, Oregon, 97045
United States
Legacy Good Samaritan Hospital and Medical Center
Portland, Oregon, 97210
United States
Providence Portland Medical Center
Portland, Oregon, 97213
United States
Providence Saint Vincent Medical Center
Portland, Oregon, 97225
United States
Saint Charles Health System-Redmond
Redmond, Oregon, 97756
United States
Legacy Meridian Park Hospital
Tualatin, Oregon, 97062
United States
Lehigh Valley Hospital-Cedar Crest
Allentown, Pennsylvania, 18103
United States
UPMC Altoona
Altoona, Pennsylvania, 16601
United States
UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania, 15009
United States
Lehigh Valley Hospital - Muhlenberg
Bethlehem, Pennsylvania, 18017
United States
Carlisle Regional Cancer Center
Carlisle, Pennsylvania, 17015
United States
Christiana Care Health System-Concord Health Center
Chadds Ford, Pennsylvania, 19317
United States
Northeast Radiation Oncology Center
Dunmore, Pennsylvania, 18512
United States
Pocono Medical Center
East Stroudsburg, Pennsylvania, 18301
United States
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, 16505
United States
UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania, 16121
United States
Fox Chase Cancer Center Buckingham
Furlong, Pennsylvania, 18925
United States
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, 15601
United States
UPMC Pinnacle Cancer Center/Community Osteopathic Campus
Harrisburg, Pennsylvania, 17109
United States
Lehigh Valley Hospital-Hazleton
Hazleton, Pennsylvania, 18201
United States
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania, 15901
United States
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania, 15132
United States
UPMC Hillman Cancer Center at Rocco And Nancy Ortenzio Cancer Pavilion
Mechanicsburg, Pennsylvania, 17050
United States
UPMC Cancer Center - Monroeville
Monroeville, Pennsylvania, 15146
United States
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania, 15146
United States
UPMC Hillman Cancer Center in Coraopolis
Moon, Pennsylvania, 15108
United States
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107
United States
Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111
United States
Temple University Hospital
Philadelphia, Pennsylvania, 19140
United States
UPMC-Magee Womens Hospital
Pittsburgh, Pennsylvania, 15213
United States
UPMC-Presbyterian Hospital
Pittsburgh, Pennsylvania, 15213
United States
UPMC-Saint Margaret
Pittsburgh, Pennsylvania, 15215
United States
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, 15232
United States
UPMC-Shadyside Hospital
Pittsburgh, Pennsylvania, 15232
United States
UPMC Jefferson Regional Radiation Oncology
Pittsburgh, Pennsylvania, 15236
United States
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, 15237
United States
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania, 15243
United States
Pottstown Hospital
Pottstown, Pennsylvania, 19464
United States
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, 16346
United States
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania, 15401
United States
UPMC Uniontown Hospital Radiation Oncology
Uniontown, Pennsylvania, 15401
United States
UPMC Cancer Center-Washington
Washington, Pennsylvania, 15301
United States
UPMC Washington Hospital Radiation Oncology
Washington, Pennsylvania, 15301
United States
Reading Hospital
West Reading, Pennsylvania, 19611
United States
UPMC Memorial
York, Pennsylvania, 17408
United States
Smilow Cancer Hospital Care Center - Westerly
Westerly, Rhode Island, 02891
United States
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina, 29316
United States
Medical University of South Carolina
Charleston, South Carolina, 29425
United States
Prisma Health Cancer Institute - Easley
Easley, South Carolina, 29640
United States
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina, 29605
United States
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, 29605
United States
Prisma Health Greenville Memorial Hospital
Greenville, South Carolina, 29605
United States
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, 29615
United States
Prisma Health Cancer Institute - Greer
Greer, South Carolina, 29650
United States
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, 29672
United States
Sanford Cancer Center Oncology Clinic
Sioux Falls, South Dakota, 57104
United States
Avera Cancer Institute
Sioux Falls, South Dakota, 57105
United States
Sanford USD Medical Center - Sioux Falls
Sioux Falls, South Dakota, 57117-5134
United States
Memorial Hospital
Chattanooga, Tennessee, 37404
United States
Pulmonary Medicine Center of Chattanooga-Hixson
Hixson, Tennessee, 37343
United States
Memorial GYN Plus
Ooltewah, Tennessee, 37363
United States
Saint Joseph Regional Cancer Center
Bryan, Texas, 77802
United States
MD Anderson in The Woodlands
Conroe, Texas, 77384
United States
Parkland Memorial Hospital
Dallas, Texas, 75235
United States
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, 75390
United States
University of Texas Medical Branch
Galveston, Texas, 77555-0565
United States
M D Anderson Cancer Center
Houston, Texas, 77030
United States
MD Anderson West Houston
Houston, Texas, 77079
United States
MD Anderson League City
League City, Texas, 77573
United States
UTMB Cancer Center at Victory Lakes
League City, Texas, 77573
United States
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas, 75080
United States
MD Anderson in Sugar Land
Sugar Land, Texas, 77478
United States
Farmington Health Center
Farmington, Utah, 84025
United States
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, 84112
United States
South Jordan Health Center
South Jordan, Utah, 84009
United States
University of Virginia Cancer Center
Charlottesville, Virginia, 22908
United States
Inova Schar Cancer Institute
Fairfax, Virginia, 22031
United States
Inova Fairfax Hospital
Falls Church, Virginia, 22042
United States
VCU Massey Cancer Center at Stony Point
Richmond, Virginia, 23235
United States
Virginia Commonwealth University/Massey Cancer Center
Richmond, Virginia, 23298
United States
VCU Community Memorial Health Center
South Hill, Virginia, 23970
United States
Providence Regional Cancer System-Aberdeen
Aberdeen, Washington, 98520
United States
PeaceHealth Saint Joseph Medical Center
Bellingham, Washington, 98225
United States
Harrison HealthPartners Hematology and Oncology-Bremerton
Bremerton, Washington, 98310
United States
Highline Medical Center-Main Campus
Burien, Washington, 98166
United States
Providence Regional Cancer System-Centralia
Centralia, Washington, 98531
United States
Swedish Cancer Institute-Edmonds
Edmonds, Washington, 98026
United States
Saint Elizabeth Hospital
Enumclaw, Washington, 98022
United States
Providence Regional Cancer Partnership
Everett, Washington, 98201
United States
Saint Francis Hospital
Federal Way, Washington, 98003
United States
Swedish Cancer Institute-Issaquah
Issaquah, Washington, 98029
United States
Kadlec Clinic Hematology and Oncology
Kennewick, Washington, 99336
United States
Providence Regional Cancer System-Lacey
Lacey, Washington, 98503
United States
Saint Clare Hospital
Lakewood, Washington, 98499
United States
PeaceHealth Saint John Medical Center
Longview, Washington, 98632
United States
Harrison HealthPartners Hematology and Oncology-Poulsbo
Poulsbo, Washington, 98370
United States
Pacific Gynecology Specialists
Seattle, Washington, 98104
United States
Swedish Medical Center-Ballard Campus
Seattle, Washington, 98107
United States
Swedish Medical Center-Cherry Hill
Seattle, Washington, 98122-5711
United States
Swedish Medical Center-First Hill
Seattle, Washington, 98122
United States
PeaceHealth United General Medical Center
Sedro-Woolley, Washington, 98284
United States
Providence Regional Cancer System-Shelton
Shelton, Washington, 98584
United States
Saint Michael Cancer Center
Silverdale, Washington, 98383
United States
Franciscan Research Center-Northwest Medical Plaza
Tacoma, Washington, 98405
United States
Northwest Medical Specialties PLLC
Tacoma, Washington, 98405
United States
PeaceHealth Southwest Medical Center
Vancouver, Washington, 98664
United States
Legacy Cancer Institute Medical Oncology and Day Treatment
Vancouver, Washington, 98684
United States
Legacy Salmon Creek Hospital
Vancouver, Washington, 98686
United States
Providence Saint Mary Regional Cancer Center
Walla Walla, Washington, 99362
United States
Providence Regional Cancer System-Yelm
Yelm, Washington, 98597
United States
West Virginia University Charleston Division
Charleston, West Virginia, 25304
United States
ThedaCare Regional Cancer Center
Appleton, Wisconsin, 54911
United States
Duluth Clinic Ashland
Ashland, Wisconsin, 54806
United States
Northwest Wisconsin Cancer Center
Ashland, Wisconsin, 54806
United States
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, 53105
United States
Aurora Saint Luke's South Shore
Cudahy, Wisconsin, 53110
United States
HSHS Sacred Heart Hospital
Eau Claire, Wisconsin, 54701
United States
Marshfield Clinic Cancer Center at Sacred Heart
Eau Claire, Wisconsin, 54701
United States
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, 54701
United States
Aurora Health Center-Fond du Lac
Fond Du Lac, Wisconsin, 54937
United States
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, 53022
United States
Aurora Cancer Care-Grafton
Grafton, Wisconsin, 53024
United States
Aurora BayCare Medical Center
Green Bay, Wisconsin, 54311
United States
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, 53142
United States
University of Wisconsin Carbone Cancer Center - University Hospital
Madison, Wisconsin, 53792
United States
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, 54143
United States
Bay Area Medical Center
Marinette, Wisconsin, 54143
United States
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, 54449
United States
Marshfield Medical Center
Marshfield, Wisconsin, 54449
United States
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, 53209
United States
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, 53215
United States
Aurora Sinai Medical Center
Milwaukee, Wisconsin, 53233
United States
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, 54548
United States
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, 54017
United States
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, 54904
United States
Aurora Cancer Care-Racine
Racine, Wisconsin, 53406
United States
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, 54868
United States
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, 53081
United States
Ascension Saint Michael's Hospital
Stevens Point, Wisconsin, 54481
United States
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, 54482
United States
Aurora Medical Center in Summit
Summit, Wisconsin, 53066
United States
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, 54241
United States
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, 53226
United States
Aurora West Allis Medical Center
West Allis, Wisconsin, 53227
United States
Diagnostic and Treatment Center
Weston, Wisconsin, 54476
United States
Marshfield Medical Center - Weston
Weston, Wisconsin, 54476
United States
Big Horn Basin Cancer Center
Cody, Wyoming, 82414
United States
Billings Clinic-Cody
Cody, Wyoming, 82414
United States
Welch Cancer Center
Sheridan, Wyoming, 82801
United States

Collaborators and Investigators

Sponsor: ECOG-ACRIN Cancer Research Group

  • Robert Ferris, PRINCIPAL_INVESTIGATOR, ECOG-ACRIN Cancer Research Group

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-11-23
Study Completion Date2027-12-31

Study Record Updates

Study Start Date2016-11-23
Study Completion Date2027-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Head and Neck Squamous Cell Carcinoma
  • Hypopharyngeal Squamous Cell Carcinoma
  • Laryngeal Squamous Cell Carcinoma
  • Laryngeal Squamous Cell Carcinoma, Spindle Cell Variant
  • Lip and Oral Cavity Squamous Cell Carcinoma
  • p16INK4a Negative Oropharyngeal Squamous Cell Carcinoma
  • Stage III Hypopharyngeal Carcinoma AJCC v8
  • Stage III Laryngeal Cancer AJCC v8
  • Stage III Lip and Oral Cavity Cancer AJCC v8
  • Stage III Oral Cavity Verrucous Carcinoma
  • Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8
  • Stage IVA Hypopharyngeal Carcinoma AJCC v8
  • Stage IVA Laryngeal Cancer AJCC v8
  • Stage IVA Lip and Oral Cavity Cancer AJCC v8
  • Stage IVA Oral Cavity Verrucous Carcinoma
  • Stage IVA Oropharyngeal (p16-Negative) Carcinoma AJCC v8