Hereditary Risk Factors for Thyroid Cancer

Description

Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules. * In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies. * Individuals with a past or present childhood thyroid cancer/nodule or a thyroid cancer suspected to be inherited in their family are invited to participate.

Conditions

Thyroid Cancer

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Study Overview

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Study Details

Study overview

Thyroid cancers can occur sporadically, but can also be found as tumors that cluster in families with other cancers or genetic syndromes. Researchers are studying thyroid cancer in children and families, with a particular interest in understanding genes and other factors that may put individuals at risk for developing thyroid cancer and thyroid nodules. * In this study, family and medical history information is collected alongside a blood or saliva sample for genetic studies. * Individuals with a past or present childhood thyroid cancer/nodule or a thyroid cancer suspected to be inherited in their family are invited to participate.

Hereditary Risk Factors for Thyroid Cancer

Hereditary Risk Factors for Thyroid Cancer

Condition
Thyroid Cancer
Intervention / Treatment

-

Contacts and Locations

Boston

Dana Farber Cancer Institute, Boston, Massachusetts, United States, 02115

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Individual pediatric patient with current or previous known or suspected thyroid cancer or nodule(s).
  • * Individual adult patient with current or previous known or suspected thyroid cancer or nodule(s) if they come from a family with a high suspicion of hereditary cancer (as below).
  • * Individuals from families with a high suspicion of hereditary thyroid cancer:
  • * Families with a current or previous diagnosis of a thyroid cancer/nodule occurring in childhood (\<18 years old).
  • * Families with a high suspicion of hereditary thyroid cancer/nodules other than above to include:
  • * Families with thyroid cancer in multiple individuals
  • * Families with thyroid cancer and a known genetic syndrome
  • * Families with thyroid cancer and a suspected genetic syndrome (e.g. multiple childhood cancers in the family, multiple primary cancers, multiple endocrinopathies, etc.)
  • * Individuals who are unable to give informed consent.
  • * Individuals who are unable to complete study materials.

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Dana-Farber Cancer Institute,

Junne Kamihara, MD, PhD, PRINCIPAL_INVESTIGATOR, Dana-Farber Cancer Institute

Study Record Dates

2029-03-01