RECRUITING

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This is an observational, non-therapeutic study to collect clinical and molecular information of pediatric patients with childhood melanocytic lesions. PRIMARY OBJECTIVE: To perform a comprehensive molecular analysis of samples either from paraffin embedded and/or frozen tissue from patients with pediatric melanocytic lesions (including melanoma, spitzoid melanoma, congenital melanoma, melanoma arising in giant nevi). SECONDARY OBJECTIVE: To collect minimal information on patients treated with adjuvant or systemic therapies according to National Comprehensive Cancer Network (NCCN) guidelines.

Official Title

Molecular Analysis of Childhood and Adolescent Melanocytic Lesions

Quick Facts

Study Start:2016-05-31
Study Completion:2041-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02775643

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Participant has a suspected or confirmed diagnosis of a melanocytic lesion, including:
  2. * Conventional or "adult-type" melanoma
  3. * Spitzoid melanoma/atypical Spitz tumor
  4. * Congenital melanoma
  5. * Melanoma arising in a giant congenital nevus
  6. * Melanocytic lesions with indeterminate biological behavior (e.g., pigment synthesizing melanomas)
  7. * Participant was \<19 years of age at the time of diagnosis.
  8. * Tissue is available for biologic studies.
  9. * Participant has been enrolled on the TBANK protocol at SJCRH, or will be enrolled before any research tests are performed on their biological materials.
  1. * Ocular melanoma
  2. * Inability or unwillingness of research participant or legal guardian to consent.
  3. * Histologic diagnosis other than melanocytic lesion described in 3.1.1.

Contacts and Locations

Study Contact

Alberto Pappo, MD
CONTACT
866-278-5835
referralinfo@stjude.org

Principal Investigator

Alberto Pappo, MD
PRINCIPAL_INVESTIGATOR
St. Jude Children's Research Hospital

Study Locations (Sites)

St. Jude Children's Research Hospital
Memphis, Tennessee, 38105
United States

Collaborators and Investigators

Sponsor: St. Jude Children's Research Hospital

  • Alberto Pappo, MD, PRINCIPAL_INVESTIGATOR, St. Jude Children's Research Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-05-31
Study Completion Date2041-05-31

Study Record Updates

Study Start Date2016-05-31
Study Completion Date2041-05-31

Terms related to this study

Keywords Provided by Researchers

  • Melanoma
  • Spitzoid Melanoma
  • Congenital Melanoma
  • Melanoma Arising in Giant Nevi
  • Melanocytic lesions with indeterminate biological behavior
  • Pigment synthesizing melanomas

Additional Relevant MeSH Terms

  • Melanoma