RECRUITING

Prospective Research Rare Kidney Stones (ProRKS)

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine the natural history of the hereditary forms of nephrolithiasis and chronic kidney disease (CKD), primary hyperoxaluria (PH), cystinuria, Dent disease and adenine phosphoribosyltransferase deficiency (APRTd) and acquired enteric hyperoxaluria (EH). The investigator will measure blood and urinary markers of inflammation and determine relationship to the disease course. Cross-comparisons among the disorders will allow us to better evaluate mechanisms of renal dysfunction in these disorders.

Official Title

Prospective Research Rare Kidney Stones (ProRKS)

Quick Facts

Study Start:2016-05
Study Completion:2026-07
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02780297

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Diagnosis of primary hyperoxaluria
  2. 2. Diagnosis of enteric hyperoxaluria
  3. 3. Diagnosis of Dent Disease
  4. 4. Diagnosis of Cystinuria
  5. 5. Diagnosis of adenine phosphoribosyltransferase deficiency (APRTd)
  6. 6. Diagnosis of Lowe Syndrome
  7. 7. Diagnosis of Dent Disease Carrier
  1. 1. Prior renal failure
  2. 2. History of liver and/or kidney transplant.

Contacts and Locations

Study Contact

Barb Seide
CONTACT
800-270-4637
RareKidneyStones@mayo.edu
Julie Olson, RN
CONTACT
800-270-4637
RareKidneyStones@mayo.edu

Principal Investigator

John Lieske, MD
PRINCIPAL_INVESTIGATOR
Mayo Clinic

Study Locations (Sites)

University of Alabama @ Birmingham
Birmingham, Alabama, 35294
United States
Mayo Clinic Jacksonville
Jacksonville, Florida, 32224
United States
Children's Memorial Hospital
Chicago, Illinois, 60614
United States
Children's Hospital, Harvard Medical School
Boston, Massachusetts, 02115
United States
Mayo Clinic Hyperoxaluria Center
Rochester, Minnesota, 55905
United States
New York University
New York, New York, 10010
United States
Cincinnati Children's Hosptial Medical Center
Cincinnati, Ohio, 45229
United States
Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • John Lieske, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-05
Study Completion Date2026-07

Study Record Updates

Study Start Date2016-05
Study Completion Date2026-07

Terms related to this study

Keywords Provided by Researchers

  • primary hyperoxaluria
  • Dent Disease
  • enteric hyperoxaluria
  • cystinuria
  • Lowe Syndrome
  • Adenine phosphoribosyltransferase deficiency
  • PH
  • APRTd
  • APRT
  • hyperoxaluria
  • oxalate
  • oxalosis
  • PH type 1
  • PH type 2
  • PH type 3
  • Dents
  • Dent
  • Dent 1
  • Dent 2
  • APRT deficiency

Additional Relevant MeSH Terms

  • Hyperoxaluria
  • Cystinuria
  • Dent Disease
  • Lowe Syndrome
  • Adenine Phosphoribosyltransferase Deficiency