RECRUITING

Diagnostic and Therapeutic Applications of Microarrays in Lung Transplantation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Objective: To evaluate the potential impact of molecular phenotyping of transbronchial biopsies in lung transplant recipients with allograft dysfunction, and the potential for developing a safer endobronchial mucosal biopsy format.

Official Title

Multi-Centric Observational Study to Analyze the Diagnostic Molecular Features in the Clinical Setting of Lung Allograft Biopsies

Quick Facts

Study Start:2016-05
Study Completion:2026-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02812290

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All lung transplant recipients undergoing a biopsy as determined by their surgeon or physician.
  1. * Patients who declined participation or unable to give informed consent.

Contacts and Locations

Study Contact

Konrad S Famulski, PhD
CONTACT
1 780 492 1725
konrad@ualberta.ca
Robert Polakowski, PhD
CONTACT
1 780 492 5091
polakows@ualberta.ca

Principal Investigator

Philip F Halloran, MD, PhD
PRINCIPAL_INVESTIGATOR
Faculty of Medicine and Dentistry, University of Alberta

Study Locations (Sites)

University of Maryland School of Medicine
Baltimore, Maryland, 21201
United States
Division of Pulmonary and Critical Care, Washington University School of Medicine
Saint Louis, Missouri, 63110
United States
University of Texas at San Antonio
San Antonio, Texas, 21201
United States

Collaborators and Investigators

Sponsor: University of Alberta

  • Philip F Halloran, MD, PhD, PRINCIPAL_INVESTIGATOR, Faculty of Medicine and Dentistry, University of Alberta

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2016-05
Study Completion Date2026-06

Study Record Updates

Study Start Date2016-05
Study Completion Date2026-06

Terms related to this study

Keywords Provided by Researchers

  • antibody mediated rejection
  • T cell mediated rejection

Additional Relevant MeSH Terms

  • Lung Transplant Rejection