The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring extracorporeal membrane oxygenation (ECMO), by direct injection of autogeneic mitochondria into the ischemic myocardium.
Extracorporeal Membrane Oxygenation Complication
The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring extracorporeal membrane oxygenation (ECMO), by direct injection of autogeneic mitochondria into the ischemic myocardium.
Transplantation of Autologously Derived Mitochondria Following Ischemia
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Boston Children's Hospital, Boston, Massachusetts, United States, 02115
Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
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to 17 Years
ALL
No
Boston Children's Hospital,
Sitaram M Emani, MD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital
2025-06