RECRUITING

Transplantation of Autologously Derived Mitochondria Following Ischemia

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The investigators propose a robust therapeutic intervention to ameliorate myocardial ischemia/ reperfusion injury and significantly decrease morbidity and mortality in patients requiring extracorporeal membrane oxygenation (ECMO), by direct injection of autogeneic mitochondria into the ischemic myocardium.

Official Title

Transplantation of Autologously Derived Mitochondria for Protection Against Ischemia-reperfusion Injury Following Ischemia in Subjects on ECMO Support

Quick Facts

Study Start:2017-08-02
Study Completion:2025-06
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT02851758

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified to 17 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD
Inclusion CriteriaExclusion Criteria
  1. * Pediatric cardiology patients under the age of 18 on ECMO
  2. * concerns for ischemic injury on the Cardiac Intensive Care Unit
  1. * Known mitochondria disorders

Contacts and Locations

Study Contact

Breanna Piekarski, RN, BSN
CONTACT
617-919-4457
breanna.piekarski@cardio.chboston.org

Principal Investigator

Sitaram M Emani, MD
PRINCIPAL_INVESTIGATOR
Boston Children's Hospital

Study Locations (Sites)

Boston Children's Hospital
Boston, Massachusetts, 02115
United States

Collaborators and Investigators

Sponsor: Boston Children's Hospital

  • Sitaram M Emani, MD, PRINCIPAL_INVESTIGATOR, Boston Children's Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-08-02
Study Completion Date2025-06

Study Record Updates

Study Start Date2017-08-02
Study Completion Date2025-06

Terms related to this study

Additional Relevant MeSH Terms

  • Extracorporeal Membrane Oxygenation Complication