Predicting Concussion Outcomes with Salivary MiRNA

Description

The purpose of this study is to identify changes in salivary ribosomal nucleic acid (RNA) expression that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.

Conditions

Concussion, Mild

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Study Overview

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Study Details

Study overview

The purpose of this study is to identify changes in salivary ribosomal nucleic acid (RNA) expression that are predictive of symptom duration and character following mild traumatic brain injury (mTBI) in children.

Predicting Concussion Outcomes with Salivary MiRNA

Predicting Concussion Outcomes with Salivary MiRNA

Condition
Concussion, Mild
Intervention / Treatment

-

Contacts and Locations

Hershey

Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania, United States, 17033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 5-21 years with mild traumatic brain injury that occurred within 7 days of enrollment
  • * Sever traumatic brain injury
  • * Skull fracture
  • * Concurrent upper respiratory infection
  • * Patients whose primary language is not English
  • * Periodontal infection
  • * Wards of the state
  • * Ongoing seizure disorder,
  • * Drug or alcohol dependency

Ages Eligible for Study

5 Years to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Milton S. Hershey Medical Center,

Steven Hicks, MD, PhD, PRINCIPAL_INVESTIGATOR, Milton S. Hershey Medical Center

Study Record Dates

2025-09