Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Description

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

Conditions

Multiple Sclerosis

Talk to us

Study Overview

On this page

Study Details

Study overview

In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Prospective Investigation of Multiple Sclerosis in the Three Rivers Region

Condition
Multiple Sclerosis
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 15260

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Inclusion criteria for MS patients include:
  • 1. willing and able to give consent
  • 2. age 7 years or older
  • 3. diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
  • * For healthy controls:
  • 1. Age 7 years or older
  • 2. Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
  • 3. No known personal history of multiple sclerosis or related disorders
  • 4. No other chronic diseases
  • 5. Family members, unrelated household controls, or controls from the general population could be eligible

Ages Eligible for Study

7 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Pittsburgh,

Zongqi Xia, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2047-01