RECRUITING

Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Tranexamic Acid (TXA) is an antifibrolytic medication used in total hip and knee arthroplasty to reduce the need for intraoperative and postoperative blood transfusions. Limited research is available on its use in hip fracture patients. We hypothesize that the use of TXA preoperatively, perioperatively, and postoperatively will decrease blood loss and need for blood transfusion postoperatively.

Official Title

Evaluating the Effect of Tranexamic Acid (TXA) on Reduction of Postoperative Blood Transfusion in Hip Fracture Patients

Quick Facts

Study Start:2017-08-30
Study Completion:2025-09-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03063892

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Over the age of 60 years
  2. * Hip fracture requiring surgical intervention
  3. * Signs consent and agrees to participate
  1. * Under the age of 60
  2. * Does not sign consent or refuses participation
  3. * Known hypersensitivity to tranexamic acid
  4. * Multiple acute fractures
  5. * Creatinine clearance \<30
  6. * History of seizures
  7. * Active hormone therapy
  8. * History of coagulation abnormality
  9. * History of deep vein thrombosis (DVT) or pulmonary embolism (PE) within the last year or history or recurrent DVT/PE
  10. * Myocardial infarction (MI) and/or stents within the past year
  11. * History of intracranial hemorrhage
  12. * Acquired defective color vision
  13. * Patients admitted directly to nursing units or surgery without stay in the Emergency Center
  14. * Patients who sustain fracture while hospitalized at ProMedica Toledo Hospital

Contacts and Locations

Study Contact

Kristin Gardner, MSN, RN
CONTACT
419-291-5927
kristin.gardner@promedica.org
Michelle Barhite, RPh
CONTACT
419-291-7709
michelle.barhite@promedica.org

Principal Investigator

Gregory M Georgiadis, MD
PRINCIPAL_INVESTIGATOR
ProMedica Toledo Hospital

Study Locations (Sites)

ProMedica Toledo Hospital
Toledo, Ohio, 43606
United States

Collaborators and Investigators

Sponsor: Gregory M Georgiadis MD

  • Gregory M Georgiadis, MD, PRINCIPAL_INVESTIGATOR, ProMedica Toledo Hospital

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-08-30
Study Completion Date2025-09-01

Study Record Updates

Study Start Date2017-08-30
Study Completion Date2025-09-01

Terms related to this study

Additional Relevant MeSH Terms

  • Hip Fractures