RECRUITING

Study of Letrozole in Recurrent Gliomas

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to determine the ability of letrozole to penetrate the blood brain barrier and concentrate in gliomas.

Official Title

A Phase 0/1 Pharmacokinetic and Pharmacodynamics and Safety and Tolerability Study of Letrozole in Combination With Standard Therapy in Recurrent High Grade Gliomas

Quick Facts

Study Start:2017-05-16
Study Completion:2024-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03122197

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

UC Cancer Center Clinical Trials Office
CONTACT
513-584-7698
cancer@uchealth.com

Principal Investigator

Trisha Wise-Draper, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Cincinnati

Study Locations (Sites)

University of Cincinnati
Cincinnati, Ohio, 45267
United States

Collaborators and Investigators

Sponsor: University of Cincinnati

  • Trisha Wise-Draper, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Cincinnati

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-05-16
Study Completion Date2024-12

Study Record Updates

Study Start Date2017-05-16
Study Completion Date2024-12

Terms related to this study

Additional Relevant MeSH Terms

  • Brain Tumor