Interventions for Postoperative Delirium: Biomarker-3

Description

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

Conditions

Delirium

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Study Overview

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Study Details

Study overview

The IPOD-B3 study aims to characterize the relationship between premorbid brain activity and postoperative delirium in patients undergoing major surgery. This is a expansion of the NeuroVISION Bolt-On study, NCT01980511.

Interventions for Postoperative Delirium: Biomarker-3

Interventions for Postoperative Delirium: Biomarker-3

Condition
Delirium
Intervention / Treatment

-

Contacts and Locations

Madison

University of Wisconsin-Madison, Madison, Wisconsin, United States, 53792

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age ≥65 years
  • * Anticipated length of hospital stay of at least 2 days after surgery that occurs under general or neuraxial anesthesia
  • * Written Informed Consent for potential participation prior to surgery
  • * Contraindication to EEG
  • * Unable or unwilling to attend the follow-up appointments
  • * Documented history of dementia
  • * Deemed incapable of providing consent by surgical team
  • * Residing in a nursing home
  • * Undergoing intracranial surgery
  • * Unable to complete neurocognitive testing due to language, vision or hearing impairment
  • * Unable to communicate with the research staff due to language barriers
  • * For optional MRI portion of the study: Contraindication to MRI (e.g., implanted devices not safe for MRI studies, claustrophobia, unable to lie flat or still)

Ages Eligible for Study

65 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Wisconsin, Madison,

Robert Pearce, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

2025-12