Regulation of Inflammatory Genes in Psoriasis

Description

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Conditions

Psoriasis, Inflammation

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Study Overview

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Study Details

Study overview

Psoriasis is a chronic and recurrent skin disorder characterized by marked inflammatory changes in the skin. An extensive cytokine network including generated by activated dendritic cells and T cells mediates the formation of psoriatic lesions. These immune-response parameters can be used as markers in the severity and management of the disease after further in-depth studies.

Regulation of Inflammatory Genes in Psoriasis

Regulation of Inflammatory Genes in Psoriasis

Condition
Psoriasis
Intervention / Treatment

-

Contacts and Locations

Birmingham

The Kirklin Clinic, Birmingham, Alabama, United States, 35294

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Clinical diagnosis of psoriasis
  • * Must be age 19 or older.
  • * Must be Fitzpatrick skin type I, II, III, IV, V, VI.
  • * Subjects who do not have photosensitive disease and are not on photosensitizing medications.
  • * Subjects with a history of keloids (who are more likely to develop hypertrophic scars following skin biopsy).
  • * Subjects who have an allergy to local anesthetics, antibiotics and/or anticoagulants.
  • * Subjects who are pregnant.

Ages Eligible for Study

19 Years to 99 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Alabama at Birmingham,

Study Record Dates

2027-04-28