RECRUITING

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Pheochromocytomas and paragangliomas are neural crest-derived tumors of the nervous system that are often inherited and genetically heterogeneous. Genetic screening is recommended for patients and their relatives, and can guide clinical decisions. However, a mutation is not found in all cases. The aims of this proposal are to: 1) to map gene(s) involved in pheochromocytoma, and 2) identify genotype-phenotype correlations in patients with pheochromocytoma/paraganglioma of various genetic origins.

Official Title

Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated Conditions

Quick Facts

Study Start:2005-10-19
Study Completion:2030-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03160274

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:Not specified
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:CHILD, ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * diagnosis of pheochromocytoma and or paraganglioma
  2. * family member with diagnosis of pheochromocytoma and or paraganglioma
  3. * diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
  4. * family member with diagnosis of a pheochromocytoma- and or paraganglioma-associated condition
  1. * unconfirmed diagnosis of pheochromocytoma and/or paraganglioma or associated condition

Contacts and Locations

Study Contact

Patricia L Dahia, MD,PhD
CONTACT
2105674866
dahia@uthscsa.edu

Principal Investigator

Patricia L Dahia, MD, PhD
PRINCIPAL_INVESTIGATOR
The University of Texas Health Science Center at San Antonio

Study Locations (Sites)

University of Texas Health Science Center
San Antonio, Texas, 78229
United States

Collaborators and Investigators

Sponsor: The University of Texas Health Science Center at San Antonio

  • Patricia L Dahia, MD, PhD, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2005-10-19
Study Completion Date2030-12-31

Study Record Updates

Study Start Date2005-10-19
Study Completion Date2030-12-31

Terms related to this study

Keywords Provided by Researchers

  • tumor suppressor gene
  • oncogene
  • mutation
  • susceptibility gene

Additional Relevant MeSH Terms

  • Pheochromocytoma
  • Paraganglioma
  • Inherited Cancer Syndrome
  • Associated Conditions
  • Kidney Neoplasms
  • Bone Cancer
  • Thyroid Neoplasms
  • Other Cancer