RECRUITING

Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

INTERLIVER is a prospective observational study of the relationship of the molecular phenotype of 300 liver transplant biopsies to the histologic phenotype and the clinical features and outcomes. A segment of a biopsy performed as standard-of-care for indications, or by center protocol, will be used for gene expression study.

Official Title

Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation, a Multicenter Study

Quick Facts

Study Start:2017-12-19
Study Completion:2026-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03193151

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * biopsy for clinical indications
  1. * no consent, pregnant women

Contacts and Locations

Study Contact

Konrad S Famulski, PhD
CONTACT
1 780 492 1725
konrad@ualberta.ca
Robert Polakowski, PhD
CONTACT
1 780 492 5091
polakows@ualberta.ca

Principal Investigator

Philip F Halloran, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Alberta

Study Locations (Sites)

University of California San Francisco, Transplant Research Unit
San Francisco, California, 94143
United States
Northwestern Memorial Hospital
Chicago, Illinois, 60611
United States
University of Maryland School of Medicine
Baltimore, Maryland, 21201
United States
Henry Ford Transplant Institute
Detroit, Michigan, 48202
United States
Vanderbilt University Medical Center, Vanderbilt Transplant Center
Nashville, Tennessee, 37232
United States
Baylor University Medical Center, Annette C. and Harold C. Simmons Transplant Institute
Dallas, Texas, 75246
United States
Transplant Surgery, VCU Medical Center
Richmond, Virginia, 23298
United States
Division of Transplant Surgery, University of Washington
Seattle, Washington, 98195
United States

Collaborators and Investigators

Sponsor: University of Alberta

  • Philip F Halloran, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Alberta

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-12-19
Study Completion Date2026-12

Study Record Updates

Study Start Date2017-12-19
Study Completion Date2026-12

Terms related to this study

Keywords Provided by Researchers

  • Liver transplant
  • global gene expression
  • molecular diagnostics

Additional Relevant MeSH Terms

  • Liver Dysfunction