Early Predictors of Necrotizing Enterocolitis in Neonates

Description

The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify neonates early in the disease process. Thus, the investigators aim to identify infants with NEC prior to the onset of symptoms to institute or test treatments in the long term to prevent the progression of the disease in these infants.

Conditions

Necrotizing Enterocolitis

Study Overview

Study Details

Study overview

The goal of this project is to identify neonates who are predisposed to Necrotizing Enterocolitis (NEC). the investigators will determine the effectiveness of non-invasive measures as well as biochemical markers to identify neonates early in the disease process. Thus, the investigators aim to identify infants with NEC prior to the onset of symptoms to institute or test treatments in the long term to prevent the progression of the disease in these infants.

Clinical Model for Early Predictors of Necrotizing Enterocolitis in Neonates

Early Predictors of Necrotizing Enterocolitis in Neonates

Condition
Necrotizing Enterocolitis
Intervention / Treatment

-

Contacts and Locations

Columbus

Nationwide Children's Hospital, Columbus, Ohio, United States, 43205

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Infants born at ≤30 weeks gestational age and/or
  • * Infants with a birth weight ≤1500 grams
  • * gestational age at birth greater than 30 weeks
  • * obvious dysmorphic syndromes
  • * any abdominal wall defect including omphalocele or gastroschisis
  • * any known intestinal atresia
  • * complex cardiac abnormalities
  • * any known lethal chromosomal abnormalities

Ages Eligible for Study

to 7 Days

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Nationwide Children's Hospital,

Oluyinka Olutoye, MD, PhD, PRINCIPAL_INVESTIGATOR, Nationwide Children's Hospital

Study Record Dates

2026-12