Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap

Description

The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (\>15 pack years) with COPD, Emphysema, and Asthma-COPD Overlap with mild to severe expiratory airflow limitation. Treatment may include short and long acting inhaled beta2agonists, short and long acting inhaled muscarinic receptor antagonists, inhaled and or oral corticosteroid, oral antibiotic, supplemental oxygen, and PDE type 4 inhibitor. In some cases, the patient may have had a history of asthma preceding the development of COPD (Asthma COPD Overlap).

Conditions

COPD, Emphysema, Asthma COPD Overlap, Emphysema

Study Overview

Study Details

Study overview

The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (\>15 pack years) with COPD, Emphysema, and Asthma-COPD Overlap with mild to severe expiratory airflow limitation. Treatment may include short and long acting inhaled beta2agonists, short and long acting inhaled muscarinic receptor antagonists, inhaled and or oral corticosteroid, oral antibiotic, supplemental oxygen, and PDE type 4 inhibitor. In some cases, the patient may have had a history of asthma preceding the development of COPD (Asthma COPD Overlap).

Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap

Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap

Condition
COPD, Emphysema, Asthma COPD Overlap
Intervention / Treatment

-

Contacts and Locations

Lakewood

Arthur F Gelb MD, Lakewood, California, United States, 90712

Lakewood

Arthur F Gelb MD, Lakewood, California, United States, 90712

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * asthma- copd overlap
  • * emphysema in smokers with smoking history \> 15 pack years
  • * COPD/ bronchitis and bronchiectasis in smokers with smoking history
  • * \>15 pack years
  • * non smokers
  • * any other pulmonary diagnosis
  • * pulmonary fibrosis

Ages Eligible for Study

30 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Gelb, Arthur F., M.D.,

Arthur F Gelb, MD, PRINCIPAL_INVESTIGATOR, Clin Prof Geffen School of Medicine at UCLA Medical Center

Arthur F Gelb, MD, STUDY_DIRECTOR, Clin Prof Geffen School of Medicine at UCLA Medical Center

Study Record Dates

2027-12-01