Use of Sensory Substitution to Improve Arm Control After Stroke

Description

Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass

Conditions

Stroke, Proprioceptive Disorders

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Study Overview

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Study Details

Study overview

Supplementing or augmenting sensory information to those who have lost proprioception after stroke could help improve functional control of the arm. Thirty subjects will be recruited to a single site to evaluate the ability of supplemental kinesthetic feedback (a form of vibrotactile stimulation) to improve motor function. Participants will be tested in performing reaching movements as well as more functional tasks such as simulated drinking from a glass

Augmenting Kinesthetic Feedback to Improve Hemiparetic Arm Control After Stroke

Use of Sensory Substitution to Improve Arm Control After Stroke

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Milwaukee

Marquette University, Milwaukee, Wisconsin, United States, 53233

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * stroke survivors who can perform our stabilization and grip modulation tasks and who
  • * had a single ischemic or hemorrhagic stroke of the middle cerebral artery (MCA) in the chronic state of recovery (\> 6 months post-stroke).
  • * ability to give informed consent and be able to follow two-stage instructions.
  • * mild-to-moderate motor impairment as assessed using the upper extremity (UE) portion of the Fugl-Meyer Motor Assessment (FM); i.e., UE-FM score between 28 and 50 (inclusive) out of a possible 66.
  • * proprioceptive deficit at the elbow in the more involved (contralesional) arm.
  • * preserved tactile sensation in either the ipsilesional arm and/or thigh.
  • * a minimal active wrist extension of 5°.
  • * Inability of subjects to give informed consent or follow two-stage instructions.
  • * subjects with a bleeding disorder.
  • * subjects with fixed contractures or a history of tendon transfer in the involved limb.
  • * subjects with a diagnosis of myasthenia gravis, amyotrophic lateral sclerosis or any disease that might interfere with neuromuscular function.
  • * subjects who are currently using or under the influence of aminoglycoside antibiotics, curare-like agents, or other agents that may interfere with neuromuscular function.
  • * subjects with a history of epilepsy.
  • * history of other psychiatric co-morbidities (e.g. schizophrenia).
  • * malignant or benign intra-axial neoplasms.
  • * concurrent illness limiting the capacity to conform to study requirements.
  • * Cardiac pacemaker, cardiac arrhythmia or history of significant cardiovascular or respiratory compromise.
  • * subjects with profound atrophy or excessive weakness of muscles in the target area(s) of testing.
  • * subjects with a systemic infection.

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Marquette University,

Robert A Scheidt, PhD, PRINCIPAL_INVESTIGATOR, Marquette University

Study Record Dates

2025-05-31