RECRUITING

Abdominal Wall Transplant

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this protocol is to determine the safety and efficacy of abdominal wall transplantation as a treatment for the reconstruction of abdominal wall defects. Abdominal wall transplantation may be performed alone or in combination with another transplant.

Official Title

Abdominal Wall Transplantation for the Reconstruction of Abdominal Wall Defects as Adjunct to Abdominal Solid Organ Transplantation

Quick Facts

Study Start:2018-05-01
Study Completion:2028-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03310905

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Candidates between 18-65 years old
  2. * Willingness and legal ability to give consent
  3. * Abdominal Wall in combination with another organ transplant: they must be eligible for the non-vascularized composite allograft organ transplant at Duke
  1. * Malignancy at evaluation or history of malignancy that precludes transplantation
  2. * Pregnancy: Women who are of childbearing potential must have a negative serum pregnancy test within 48 hours of transplant and agree to use reliable contraception with two contraceptive methods for a minimum of 2 years following abdominal wall transplantation. Subjects seeking to become pregnant following 2 years will be made aware during the consent process that the effect of pregnancy on the transplanted abdominal wall and vice versa is unknown.
  3. * Medical exclusion criteria for general anesthesia
  4. * Ongoing substance abuse or history of untreated substance abuse

Contacts and Locations

Study Contact

Linda Cendales, MD
CONTACT
919-681-7514
linda.cendales@duke.edu
Kadiyala Ravindra, MD
CONTACT
919-613-9687
kadiyala.ravindra@duke.edu

Principal Investigator

Linda Cendales, MD
PRINCIPAL_INVESTIGATOR
Duke University
Kadiyala Ravindra, MD
PRINCIPAL_INVESTIGATOR
Duke University

Study Locations (Sites)

Duke University Medical Center
Durham, North Carolina, 27710
United States

Collaborators and Investigators

Sponsor: Duke University

  • Linda Cendales, MD, PRINCIPAL_INVESTIGATOR, Duke University
  • Kadiyala Ravindra, MD, PRINCIPAL_INVESTIGATOR, Duke University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-05-01
Study Completion Date2028-06-01

Study Record Updates

Study Start Date2018-05-01
Study Completion Date2028-06-01

Terms related to this study

Keywords Provided by Researchers

  • Research
  • Transplant
  • Abdominal Wall
  • Hernia

Additional Relevant MeSH Terms

  • Transplant;Failure,Kidney
  • Transplant; Failure, Liver
  • Transplant; Failure, Bowel
  • Abdominal Wall Defect
  • Abdominal Wall Fistula
  • Abdominal Wall Hernia
  • Abdominal Wall Injury