Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Description

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.

Conditions

Supine Hypertension, Autonomic Failure

Study Overview

Study Details

Study overview

Supine hypertension is a common problem that affects at least 50% of patients with primary autonomic failure. Supine hypertension can be severe and complicates the treatment of orthostatic hypotension. The purpose of this study is to assess whether continuous positive airway pressure (CPAP) decreases blood pressure in autonomic failure patients with supine hypertension.

Treatment of Supine Hypertension in Autonomic Failure with Continuous Positive Airway Pressure

Treatment of Supine Hypertension in Autonomic Failure (CPAP)

Condition
Supine Hypertension
Intervention / Treatment

-

Contacts and Locations

Nashville

Autonomic Dysfunction Center/ Vanderbilt University Medical Center, Nashville, Tennessee, United States, 37232

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients with autonomic failure and with supine hypertension from all races
  • * All medical students
  • * Pregnant women
  • * High-risk patients (e.g. heart failure, symptomatic coronary artery disease, liver impairment, history of stroke or myocardial infarction)
  • * History of serious allergies or asthma.

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Vanderbilt University Medical Center,

Italo Biaggioni, MD, PRINCIPAL_INVESTIGATOR, Vanderbilt University Medical Center

Study Record Dates

2026-12-21