RECRUITING

Cortical Spreading Depolarization After Severe Traumatic Brain Injury

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Preliminary evaluation of electrodes placed on the brain for recording brain activity and novel algorithms to determine cortical spreading depolarization foci of origination following severe traumatic brain injury requiring neurosurgical intervention.

Official Title

Cortical Spreading Depolarization After Severe Traumatic Brain Injury

Quick Facts

Study Start:2019-08-14
Study Completion:2025-11-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03321370

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patient recommended to undergo craniectomy or craniotomy for the treatment of acute TBI
  1. * Wound determined to be contaminated
  2. * Decompression is performed only in the posterior fossa
  3. * Known systemic infection
  4. * Pregnancy

Contacts and Locations

Study Contact

Samuel W Cramer, MD, PhD
CONTACT
612-624-6666
rnl@umn.edu
David P Darrow, MD, MPH
CONTACT
612-624-6666
rnl@umn.edu

Principal Investigator

Samuel W Cramer, MD, PhD
PRINCIPAL_INVESTIGATOR
University of Minnesota Neurosurgery Department; Division of Neurosurgery, Department of Surgery, Hennepin County Medical Center

Study Locations (Sites)

Hennepn Healthcare
Minneapolis, Minnesota, 55404
United States

Collaborators and Investigators

Sponsor: Hennepin County Medical Center, Minneapolis

  • Samuel W Cramer, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Minnesota Neurosurgery Department; Division of Neurosurgery, Department of Surgery, Hennepin County Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2019-08-14
Study Completion Date2025-11-01

Study Record Updates

Study Start Date2019-08-14
Study Completion Date2025-11-01

Terms related to this study

Additional Relevant MeSH Terms

  • Traumatic Brain Injury