ACTIVE_NOT_RECRUITING

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Lithium is highly effective in the treatment of bipolar disorder. This study aims to investigate, for the first time, the impact of lithium monotherapy on the structural and functional connectivity of the brain using MRI imaging.

Official Title

Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder

Quick Facts

Study Start:2017-12-07
Study Completion:2025-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:ACTIVE_NOT_RECRUITING

Study ID

NCT03336918

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Principal Investigator

Amit Anand, MD
PRINCIPAL_INVESTIGATOR
The Cleveland Clinic

Study Locations (Sites)

Cleveland Clinic Foundation Center for Behavioral Health
Cleveland, Ohio, 44195
United States

Collaborators and Investigators

Sponsor: Brigham and Women's Hospital

  • Amit Anand, MD, PRINCIPAL_INVESTIGATOR, The Cleveland Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-12-07
Study Completion Date2025-12-01

Study Record Updates

Study Start Date2017-12-07
Study Completion Date2025-12-01

Terms related to this study

Keywords Provided by Researchers

  • Bipolar Disorder
  • Bipolar I and II Depression
  • Lithium
  • Depression

Additional Relevant MeSH Terms

  • Bipolar Disorder
  • Bipolar I Depression
  • Bipolar II Depression
  • Bipolar Depression
  • Depression
  • Major Depressive Episode