RECRUITING

Long-term Follow-up Study of Patients Receiving CAR-T Cells

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This protocol is designed as a long-term follow-up study of participants who will receive CAR-T cells as part of a clinical trial at the Medical College of Wisconsin/ Froedtert Hospital. The clinical trials include the following: Phase 1 Study of CAR-20/19-T Cells in Patients with Relapsed Refractory B Cell Malignancies (NCT03019055); Phase I Trial of BCMA-TGF-BETA CAR-T Cells in Relapsed, Refractory Myeloma (NCT05976555); CAR20.19.22 T-cells in Relapsed, Refractory B-cell Malignancies (NCT05094206); LV20.19 CAR T-Cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies (NCT05990465); CAR-20/19-T Cells in Patients With Relapsed Refractory B Cell Malignancies (NCT04186520)

Official Title

Long-term Follow-up Study of Patients Receiving CAR-T Cells

Quick Facts

Study Start:2017-12-01
Study Completion:2035-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03375619

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All participants who enrolled in a CAR-T study at Froedtert Hospital \& the Medical College of Wisconsin.
  1. * There are no exclusion criteria for this study.

Contacts and Locations

Study Contact

Medical College of Wisconsin Clinical Cancer Center
CONTACT
414-805-8900
cccto@mcw.edu

Principal Investigator

Nirav Shah
PRINCIPAL_INVESTIGATOR
Medical College of Wisconsin

Study Locations (Sites)

Froedtert Hospital & Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States

Collaborators and Investigators

Sponsor: Medical College of Wisconsin

  • Nirav Shah, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-12-01
Study Completion Date2035-01-01

Study Record Updates

Study Start Date2017-12-01
Study Completion Date2035-01-01

Terms related to this study

Keywords Provided by Researchers

  • CAR-T Cell Therapy
  • chimeric antigen receptor

Additional Relevant MeSH Terms

  • Chronic Lymphocytic Leukemia
  • Lymphomas Non-Hodgkin's B-Cell
  • Lymphoma, Small Lymphocytic
  • Mantle Cell Lymphoma
  • Central Nervous System Lymphoma
  • Diffuse Large B Cell Lymphoma
  • Follicular Lymphoma
  • Burkitt Lymphoma
  • Multiple Myeloma