RECRUITING

In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach

Official Title

In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells in Healthy Subjects Using Stable Isotope Resolved Metabolomics: A Pilot Study

Quick Facts

Study Start:2017-09-01
Study Completion:2026-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03384108

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * Ages 18-60
  2. * Able to provide written consent
  1. * Renal Failure
  2. * Pregnancy
  3. * Active steroid use
  4. * Active liver Disease
  5. * Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women)
  6. * H/O alcohol use (average \> 2 drinks per day)
  7. * BMI \> 30

Contacts and Locations

Study Contact

Wilson Gonsalves
CONTACT
5072842511
gonsalves.wilson@mayo.edu

Principal Investigator

Wilson Gonsalves, MD
PRINCIPAL_INVESTIGATOR
Mayo Clinic

Study Locations (Sites)

Mayo Clinic
Rochester, Minnesota, 55905
United States

Collaborators and Investigators

Sponsor: Mayo Clinic

  • Wilson Gonsalves, MD, PRINCIPAL_INVESTIGATOR, Mayo Clinic

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2017-09-01
Study Completion Date2026-01

Study Record Updates

Study Start Date2017-09-01
Study Completion Date2026-01

Terms related to this study

Additional Relevant MeSH Terms

  • Healthy