COMPLETED

Peripheral Nerve Blocks for Above-the-knee Amputations

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Surgery performed with nerve blocks and sedation may be safer and provide better pain control compared to general anesthesia and opioid therapy in high-risk patient populations such as elderly and troubled with peripheral vascular disease, diabetes, hypertension, coronary artery disease, and chronic obstructive pulmonary disease (COPD).

Official Title

Peripheral Nerve Blocks for Upper Leg Amputations

Quick Facts

Study Start:2018-02-09
Study Completion:2024-12-18
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT03404180

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients undergoing above-the-knee amputation or knee disarticulation
  2. * Ability to understand and provide informed consent
  1. * Patient refusal or inability to provide informed consent
  2. * True allergy, not sensitivity, to any of the following substances:
  3. * \- Local anesthetics
  4. * \- Propofol or other sedative agents
  5. * \- General anesthetic agents
  6. * Pregnancy
  7. * Severe hepatic impairment
  8. * Evidence of infection at or near the proposed needle insertion site
  9. * Any sensorimotor deficit, whether acute or chronic, as determined by the PI
  10. * Chronic use of opioid medication
  11. * BMI ≥ 35

Contacts and Locations

Principal Investigator

José R Soberón, MD
PRINCIPAL_INVESTIGATOR
Malcom Randall VA Medical Center

Study Locations (Sites)

University of Florida
Gainesville, Florida, 32611
United States

Collaborators and Investigators

Sponsor: University of Florida

  • José R Soberón, MD, PRINCIPAL_INVESTIGATOR, Malcom Randall VA Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-02-09
Study Completion Date2024-12-18

Study Record Updates

Study Start Date2018-02-09
Study Completion Date2024-12-18

Terms related to this study

Additional Relevant MeSH Terms

  • Peripheral Vascular Diseases
  • Hyperglycaemia (Diabetic)
  • Hypertension
  • Coronary Artery Disease
  • Pulmonary Disease, Chronic Obstructive