RECRUITING

Continuous Positive Airway Pressure Device or Deep Inspiration Breath Hold in Reducing Tumor Motion in Patients Undergoing Stereotactic Body Radiation Therapy for Lung Cancer

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This pilot phase I/II trial studies how well a continuous positive airway pressure device or deep inspiration breath hold works in reducing tumor movement in patients undergoing stereotactic body radiation therapy (SBRT) for lung cancer. The continuous positive airway pressure device works by blowing air into the lungs while patients wear a face mask or nozzle to help expand their airways and lungs. Deep inspiration breath hold is a standard technique that uses active breath-holding to restrict movement of the body. Using a continuous positive airway pressure device may work better than deep inspiration breath hold in lowering the amount of tumor movement during stereotactic radiation body therapy.

Official Title

Measuring the Effectiveness of a Continuous Positive Airway Pressure (CPAP) Device to Reduce Tumor Motion and Increase Lung Volume Expansion in Patients Undergoing Stereotactic Body Radiotherapy (SBRT) for Tumors That Move With Respiration

Quick Facts

Study Start:2018-03-16
Study Completion:2028-05-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT03422302

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * The patient will receive stereotactic body radiotherapy in the Thoracic Radiation Oncolcogy Service at MD Anderson.
  1. * The patient has a contra-indication for using a CPAP device.
  2. * The patient has not signed a study-specific informed consent for this study.
  3. * The patient is uncooperative.
  4. * The patient has reduced consciousness.
  5. * The patient has sustained trauma or burns to the face.
  6. * The patient has undergone any facial, esophageal, gastric or sinus surgery within the last 3 months.
  7. * The patient has idiopathic pulmonary fibrosis (IPF) as documented in their medical history.
  8. * Adults who are unable to consent, individuals who are not yet adults, pregnant women and prisoners will be excluded from this study.

Contacts and Locations

Study Contact

Julianne M. Pollard, PHD
CONTACT
713-563-2591
JMPollard@mdanderson.org

Principal Investigator

Julianne M Pollard
PRINCIPAL_INVESTIGATOR
M.D. Anderson Cancer Center

Study Locations (Sites)

M D Anderson Cancer Center
Houston, Texas, 77030
United States

Collaborators and Investigators

Sponsor: M.D. Anderson Cancer Center

  • Julianne M Pollard, PRINCIPAL_INVESTIGATOR, M.D. Anderson Cancer Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2018-03-16
Study Completion Date2028-05-31

Study Record Updates

Study Start Date2018-03-16
Study Completion Date2028-05-31

Terms related to this study

Additional Relevant MeSH Terms

  • Lung Carcinoma
  • Malignant Respiratory Tract Neoplasm
  • Metastatic Malignant Neoplasm in the Lung