Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

Description

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one infusion of GM T cells will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.

Conditions

Neoplasms

Study Overview

Study Details

Study overview

This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T-cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one infusion of GM T cells will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.

Long-Term Follow-up Protocol for Subjects Treated With Gene-Modified T Cells

Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells

Condition
Neoplasms
Intervention / Treatment

-

Contacts and Locations

Birmingham

University of Alabama Birmingham, Birmingham, Alabama, United States, 10016

Gilbert

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States, 85234

Phoenix

Mayo Clinic Phoenix, Phoenix, Arizona, United States, 85054

Scottsdale

Arizona Cancer Center, Scottsdale, Arizona, United States, 85258

Tucson

Local Institution - 01021, Tucson, Arizona, United States, 85724

Duarte

City Of Hope, Duarte, California, United States, 91010

La Jolla

University Of California San Diego Moores Cancer Center, La Jolla, California, United States, 92093

Los Angeles

Local Institution - 01206, Los Angeles, California, United States, 90048

Sacramento

Local Institution - 01043, Sacramento, California, United States, 95816

San Francisco

University of California, San Francisco- California, San Francisco, California, United States, 94143

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Received at least one gene-modified (GM) T-cell infusion in a previous Celgene sponsored or Celgene alliance partner-sponsored trial, and have discontinued, or completed the post-treatment follow-up period in the parent treatment protocol, as applicable.
  • * Must understand and voluntarily sign an Informed Consent Form/Informed Assent Form prior to any study-related assessments/procedures being conducted.

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Celgene,

Bristol-Myers Squibb, STUDY_DIRECTOR, Bristol-Myers Squibb

Study Record Dates

2036-11-30